2025
April
- Congratulations to Kristian Doyle, PhD, on your promotion to Professor.
2024
December
- Analisa Stewart was awarded the American Heart Association predoctoral fellowship.
July
- Welcome Sangeetha Senthil Kumar to the Doyle lab.
June
- Welcome Analisa Stewart to the Doyle lab.
May
Update to Award - The lab has received an R56/RF1 to investigate inflammation and delayed cogntive dysfunction after stroke.
2023
November
- Sanna's paper Boosting Mitochondrial Biogenesis Diminishes Foam Cell Formation in the Post-Stroke Brain in the International Journal of Molecular Sciences, https://www.mdpi.com/1422-0067/24/23/16632
June
- Jacob C. Zbesko paper on Targeting foam cell formation to improve recovery from ischemic stroke in Neurobiology of Disease https://doi.org/10.1016/j.nbd.2023.106130
February
- Sanna's paper on Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke in the Journal of Cerebral Blood Flow & Metabolism https://journals.sagepub.com/doi/10.1177/0271678X231157298
2022
July
- Notice of Award! The lab has received an R56 to investigate inflammation and delayed cogntive dysfunction after stroke
February
- Vivian’s paper on the use of the p75 neurotrophin receptor modulator, LM11A-31, to improve recovery from stroke is published in The Journal of Pharmacology and Experimental Therapeutics https://pubmed.ncbi.nlm.nih.gov/34893553/
January
- Danielle’s paper on the use of 2-hydroxypropyl-beta-cyclodextrin to target cholesterol overload and treat the chronic inflammatory response to stroke is published in The Journal of Neuroscience https://pubmed.ncbi.nlm.nih.gov/34819339/
2021
October
- Our neurofilament light biomarker collaboration with Dr. Meredith Hay is published at the Journal of Neuroinflammation https://pubmed.ncbi.nlm.nih.gov/34654436/
- Notice of Award! The Precision Aging Network: Closing the Gap Between Cognitive Healthspan and Human Lifespan U19 Award is funded. Our lab will be helping with the molecular profile/biomarker discovery component of this project under the leadership of Dr. Carol Barnes and Dr. Matt Huentelman
August
- Notice of Award! Britt is awarded an appointment on the University of Arizona Translational Research in Alzheimer’s Disease and Related Dementias (AZ-TRADD) predoctoral training grant
July
- Kylie Calderon leaves us to start her new life as a medical student at Duke University School of Medicine
June
- Boaz Maiyo, Elizabeth Le, and Kristos Johnson join the lab as our new crop of undergraduate researchers
April
- Erin Chapman joins the lab as our new Research Technician and soon to be Master’s student
March
- Britt Gratreak joins the lab as our new MD/PhD graduate student. She will be leading our research focused on developing treatments for stroke in sickle cell disease
January
- Jacob Zbesko leaves the lab to start the next stage of his career as a postdoctoral scholar at UCSD
2020
December
- Jacob’s paper on B cells and IgA natural antibodies in stroke is published in Brain, Behavior and Immunity https://pubmed.ncbi.nlm.nih.gov/32956832/
November
- Our ketamine as a treatment for L-DOPA-induced dyskinesia in Parkinson’s disease collaboration with Dr. Torsten Falk is published in Experimental Neurology https://pubmed.ncbi.nlm.nih.gov/32717354/
2019
November
- Kristian's review of immunological mechanisms in poststroke dementia is published in Current Opinion in Neurology https://www.ncbi.nlm.nih.gov/pubmed/31789707
October
- Sanna Loppi joins the lab as our new postdoctoral researcher
September
- Notice of Award! Vivian's R01 to investigate interactions between the chronic sequelae of stroke and Alzheimer's disease is funded
- Danielle is appointed to the Immunobiology Department's Infection and Inflammation as Drivers of Aging Predoctoral Training Grant
August
- Danielle passes her qualifying exam
- Notice of Award! In collaboration with Dean Rick Schnellmann the lab receives a 4 year Veteran's Administration Merit Award to study the effects of Fomoterol on stroke recovery
July
- Kristian is promoted to Associate Professor with Tenure
May
- Rachael Hearne joins the lab as a new Research Technician
- Notice of Award! The Fondation Lequcq is funding our Transatlantic Network of Excellence Application and so The Stroke IMPaCT (STroke - Immune Mediated Pathways and Cognitive Trajectory) Network is born!
- Frankie Garcia joins the lab as part of the Undergraduate Biology Research Program (UBRP)
March
- Notice of Award! Vivian receives an R21 Award from the National Institute of Aging
- Jacob receives his third ARCS Foundation Scholarship https://www.arcsfoundation.org/about-arcs-scholars
February
- Amanda and Jen’s article is selected as a “Reader Pick” and featured on the eNeuro Blog! http://blog.eneuro.org/2019/02/Readers-Pick-1-Feb
2018
September
- Vivian’s paper is published in Acta Neuropathologica Communications. This paper links the development of Alzheimer's disease pathology following stroke with a BACE1 dependent myelin repair mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154927/
- Amanda and Jen’s paper is published in eNeuro. This is the first paper to show that the high cholesterol content of the brain may be responsible for the chronic inflammatory response to stroke https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223114/
August
- Megan begins her Ph.D program at the University of California, San Diego
- Kylie Calderon joins the lab as part of the Undergraduate Biology Research Program (UBRP)
February
- Jacob receives his second ARCS Foundation Scholarship https://www.arcsfoundation.org/about-arcs-scholars
January
- Jacob gets his first author manuscript, “Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts”, published in Neurobiology of Disease. This is the first paper to show that chronic immune responses occurring within stroke infarcts are imperfectly sequestered from the rest of the brain by glial scars https://www.ncbi.nlm.nih.gov/pubmed/29331263
- Danielle Becktel joins the research team
2017
December
- Amanda gets accepted into medical school at the University of Arizona
September
- Notice of Award! Jacob receives a F31 Research Fellowship Award from the National Institute of Neurological Disorders and Stroke
April
- Vivian is featured in a Science Select article http://www.selectscience.net/editorial-articles/husband-and-wife-duo-com...
March
- Jacob passes his qualifying Exam
February
- Jacob receives an ARCS Foundation Scholarship https://www.arcsfoundation.org/about-arcs-scholars
- Dr. Doyle in Future Medicine http://www.futuremedicine.com/doi/abs/10.2217/fnl.15.47
2016
December
- Kristina Stepanovic receives the Outstanding Senior Award from the College of Science, 2016
November
- Kristina Stepanovic receives the Outstanding Senior Award from the Department of Psychology, 2016
August
- Notice of Award! the lab's first R01 is funded
- Alex Urzua starts medical school at the University of Arizona College of Medicine - Tucson
May
- Jusine Mona joins the research team as part of the Undergraduate Biology Research Program Neuroscience and Cognitive Science Summer Research Program
January
- Kristian receives the Undergraduate Biology Research Program Outstanding Mentor Award
2015
October
- Kristian and Vivian present a webinar for Science titled: Advancing Immunology: Untangling biomarkers in the brain: http://webinar.sciencemag.org/webinar/archive/advancing-neuroimmunology
August
- Omar Hussein starts Medical School!
June
- Karen Rico joins the research team as part of the Pre-Medical Admissions Pathway Program
May
- Maj Krumberger joins the research team as part of the Neuroscience and Cognitive Science Summer Research Program
- Megan Hayes joins the research team as part of the Undergraduate Biology Research Program Neuroscience and Cognitive Science Summer Research Program
February
- Kristian and his former Post-Doctoral Advisor, Dr. Marion Buckwalter, connect delayed dementia after stroke with the presence of chronic inflammation in the brain for the first time http://www.jneurosci.org/content/35/5/2133/tab-article-info
The paper is promoted on Twitter by the director NINDS! https://twitter.com/NINDSdirector/status/563083816831823872
January
- Kristian is a runner-up for the Undergraduate Biology Research Program Outstanding Mentor Award
- Alex Urzua joins the research team via the Arizona Mentors Program
2014
May
- Omar Hussein and Kristina Stepanovic join the laboratory as part of the Neuroscience and Cognitive Science Summer Research Program
2013
October
- Vivian Nguyen and Jen Frye join the lab
September
- The Doyle Lab begins!