Publications

2019

Passalacqua, K. D., J. G. Purdy, and C. E. Wobus, "The inert meets the living: The expanding view of metabolic alterations during viral pathogenesis.", PLoS Pathog, vol. 15, issue 7, pp. e1007830, 2019 Jul. PMCID: PMC6657903  PMID: 31344128
Xi, Y., S. Harwood, L. Wise, and J. G. Purdy, "Human Cytomegalovirus pUL37x1 is Important to Remodeling of Host Lipid Metabolism.", J Virol, 2019 Aug 07. PMID: 31391267

2017

Leng, S. X., J. Kamil, J. G. Purdy, N. A. Lemmermann, M. J. Reddehase, and F. D. Goodrum, "Recent advances in CMV tropism, latency, and diagnosis during aging.", Geroscience, vol. 39, issue 3, pp. 251-259, 2017 06. PMCID: PMC5505884  PMID: 28681110

2015

Purdy, J. G., T. Shenk, and J. D. Rabinowitz, "Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication.", Cell Rep, vol. 10, issue 8, pp. 1375-85, 2015 Mar 3. PMCID: PMC4354725  PMID: 25732827

2014

Hwang, J., J. G. Purdy, K. Wu, J. D. Rabinowitz, and T. Shenk, "Estrogen-related receptor α is required for efficient human cytomegalovirus replication.", Proc Natl Acad Sci U S A, vol. 111, issue 52, pp. E5706-15, 2014 Dec 30. PMCID: PMC4284536  PMID: 25512541
England, M. R., J. G. Purdy, I. J. Ropson, P. M. Dalessio, and R. C. Craven, "Potential role for CA-SP in nucleating retroviral capsid maturation.", J Virol, vol. 88, issue 13, pp. 7170-7, 2014 Jul. PMCID: PMC4054415  PMID: 24719425

2013

Grady, S. L., J. G. Purdy, J. D. Rabinowitz, and T. Shenk, "Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection.", Proc Natl Acad Sci U S A, vol. 110, issue 51, pp. E5006-15, 2013 Dec 17. PMCID: PMC3870743  PMID: 24297925
Koyuncu, E., J. G. Purdy, J. D. Rabinowitz, and T. Shenk, "Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny.", PLoS Pathog, vol. 9, issue 5, pp. e1003333, 2013. PMCID: PMC3656100  PMID: 23696731

2011

Rabinowitz, J. D., J. G. Purdy, L. Vastag, T. Shenk, and E. Koyuncu, "Metabolomics in drug target discovery.", Cold Spring Harb Symp Quant Biol, vol. 76, pp. 235-46, 2011. PMCID: PMC4084595  PMID: 22114327

2010

Butan, C., P. M. Lokhandwala, J. G. Purdy, G. Cardone, R. C. Craven, and A. C. Steven, "Suppression of a morphogenic mutant in Rous sarcoma virus capsid protein by a second-site mutation: a cryoelectron tomography study.", J Virol, vol. 84, issue 13, pp. 6377-86, 2010 Jul. PMCID: PMC2903260  PMID: 20427531

2009

Purdy, J. G., J. M. Flanagan, I. J. Ropson, and R. C. Craven, "Retroviral capsid assembly: a role for the CA dimer in initiation.", J Mol Biol, vol. 389, issue 2, pp. 438-51, 2009 Jun 5. PMCID: PMC2996723  PMID: 19361521
Cardone, G., J. G. Purdy, N. Cheng, R. C. Craven, and A. C. Steven, "Visualization of a missing link in retrovirus capsid assembly.", Nature, vol. 457, issue 7230, pp. 694-8, 2009 Feb 5. PMCID: PMC2721793  PMID: 19194444

2008

Purdy, J. G., J. M. Flanagan, I. J. Ropson, K. E. Rennoll-Bankert, and R. C. Craven, "Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly.", J Virol, vol. 82, issue 12, pp. 5951-61, 2008 Jun. PMCID: PMC2395126  PMID: 18400856