Publications

2023

Jones, A. C., J. Leffler, I. A. Laing, J. Bizzintino, S-K. Khoo, P. N. LeSouef, P. D. Sly, P. G. Holt, D. H. Strickland, and A. Bosco, "LPS binding protein and activation signatures are upregulated during asthma exacerbations in children.", Respir Res, vol. 24, issue 1, pp. 184, 2023 Jul 12. PMCID: PMC10337076  PMID: 37438758
M Morales, L. Orozco, C. A. Rinaldi, E. de Jong, S. M. Lansley, Y. C. Gary Lee, R. M. Zemek, A. Bosco, R. A. Lake, and J. W Lesterhuis, "Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma.", PLoS One, vol. 18, issue 5, pp. e0274364, 2023. PMCID: PMC10162533  PMID: 37146029
Bosco, A., "Emerging role for interferons in respiratory viral infections and childhood asthma.", Front Immunol, vol. 14, pp. 1109001, 2023. PMCID: PMC9989033  PMID: 36895568
Tu, X., H. M. Gomez, R. Y. Kim, A. C. Brown, E. de Jong, I. Galvao, A. Faiz, A. Bosco, J. C. Horvat, P. Hansbro, et al., "Airway and parenchyma transcriptomics in a house dust mite model of experimental asthma.", Respir Res, vol. 24, issue 1, pp. 32, 2023 Jan 25. PMCID: PMC9878882  PMID: 36698141
Read, J. F., M. Serralha, J. D. Armitage, M. Munir Iqbal, M. N. Cruickshank, A. Saxena, D. H. Strickland, J. Waithman, P. G. Holt, and A. Bosco, "Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years.", Front Immunol, vol. 14, pp. 1275937, 2023. PMCID: PMC10619903  PMID: 37920467

2022

Troy, N. M., D. Strickland, M. Serralha, E. de Jong, A. C. Jones, J. Read, S. Galbraith, Z. Islam, P. Kaur, K. T. Mincham, et al., "Protection against severe infant lower respiratory tract infections by immune training: Mechanistic studies.", J Allergy Clin Immunol, vol. 150, issue 1, pp. 93-103, 2022 Jul. PMID: 35177255
Tilsed, C. M., T. H. Casey, E. de Jong, A. Bosco, R. M. Zemek, J. Salmons, G. Wan, M. J. Millward, A. K. Nowak, R. A. Lake, et al., "Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy.", Front Oncol, vol. 12, pp. 849793, 2022. PMCID: PMC8988133  PMID: 35402250
Lee, K. Hung, A. Bosco, M. O'Sullivan, Y. Song, J. Metcalfe, K. Yu, B. J. Mullins, R. Loh, and G. Zhang, "Identifying gene network patterns and associated cellular immune responses in children with or without nut allergy.", World Allergy Organ J, vol. 15, issue 2, pp. 100631, 2022 Feb. PMCID: PMC8844301  PMID: 35228856
M Morales, L. Orozco, C. A. Rinaldi, E. de Jong, S. M. Lansley, J. P. A. Gummer, B. Olasz, S. Nambiar, D. E. Hope, T. H. Casey, Y. C. Gary Lee, et al., "PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective.", iScience, vol. 25, issue 1, pp. 103571, 2022 Jan 21. PMCID: PMC8692993  PMID: 34984327
Ashley, S. E., A. C. Jones, D. Anderson, P. G. Holt, A. Bosco, and M. L. K. Tang, "Remission of peanut allergy is associated with rewiring of allergen-driven T helper 2-related gene networks.", Allergy, vol. 77, issue 10, pp. 3015-3027, 2022 Oct. PMCID: PMC9790273  PMID: 35615783
Tu, X., R. Y. Kim, A. C. Brown, E. de Jong, B. Jones-Freeman, M. Khadem Ali, H. M. Gomez, K. F. Budden, M. R. Starkey, G. J. M. Cameron, et al., "Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap.", J Allergy Clin Immunol, vol. 150, issue 4, pp. 817-829.e6, 2022 Oct. PMID: 35643377
Zemek, R. M., W. Loong Chin, V. S. Fear, B. Wylie, T. H. Casey, C. Forbes, C. M. Tilsed, L. Boon, B. B. Guo, A. Bosco, et al., "Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice.", Nat Commun, vol. 13, issue 1, pp. 4895, 2022 Aug 19. PMCID: PMC9390963  PMID: 35986006
Read, J. F., M. Serralha, D. Mok, B. J. Holt, M. Cruickshank, Y. V. Karpievitch, D. I. Broadhurst, P. D. Sly, D. H. Strickland, S. N. Reinke, et al., "Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life.", Front Immunol, vol. 13, pp. 876654, 2022. PMCID: PMC9389556  PMID: 35990635

2021

Armitage, J. D., H. V. Newnes, A. McDonnell, A. Bosco, and J. Waithman, "Fine-Tuning the Tumour Microenvironment: Current Perspectives on the Mechanisms of Tumour Immunosuppression.", Cells, vol. 10, issue 1, 2021 Jan 01. PMCID: PMC7823446  PMID: 33401460
Coleman, L. A., S-K. Khoo, K. Franks, F. Prastanti, P. Le Souëf, Y. V. Karpievitch, I. A. Laing, and A. Bosco, "Personal Network Inference Unveils Heterogeneous Immune Response Patterns to Viral Infection in Children with Acute Wheezing.", J Pers Med, vol. 11, issue 12, 2021 Dec 03. PMCID: PMC8706513  PMID: 34945765
Newnes, H. V., J. D. Armitage, K. M. Audsley, A. Bosco, and J. Waithman, "Directing the Future Breakthroughs in Immunotherapy: The Importance of a Holistic Approach to the Tumour Microenvironment.", Cancers (Basel), vol. 13, issue 23, 2021 Nov 24. PMCID: PMC8656826  PMID: 34885021
McGrath, F. Marina, A. Francis, D. M. Fatovich, S. P. J. Macdonald, G. Arendts, A. Bosco, A. Woo, and E. Bosio, "Small nucleolar RNA networks are up-regulated during human anaphylaxis.", Clin Exp Allergy, vol. 51, issue 10, pp. 1310-1321, 2021 Oct. PMID: 34228845
Ralph, A. P., R. Webb, N. J. Moreland, R. McGregor, A. Bosco, D. Broadhurst, T. Lassmann, T. C. Barnett, R. Benothman, J. Yan, et al., "Searching for a technology-driven acute rheumatic fever test: the START study protocol.", BMJ Open, vol. 11, issue 9, pp. e053720, 2021 Sep 15. PMCID: PMC8444258  PMID: 34526345
Audsley, K. M., T. Wagner, C. Ta, H. V. Newnes, A. C. Buzzai, S. A. Barnes, B. Wylie, J. Armitage, T. Kaisho, A. Bosco, et al., "IFNβ Is a Potent Adjuvant for Cancer Vaccination Strategies.", Front Immunol, vol. 12, pp. 735133, 2021. PMCID: PMC8450325  PMID: 34552594
de Jong, E., J-F. Lauzon-Joset, J. Leffler, M. Serralha, A. N. Larcombe, C. T. Christophersen, P. G. Holt, D. H. Strickland, and A. Bosco, "IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming.", Front Immunol, vol. 12, pp. 699633, 2021. PMCID: PMC8339879  PMID: 34367159
de Jong, E., and A. Bosco, "Unlocking immune-mediated disease mechanisms with transcriptomics.", Biochem Soc Trans, vol. 49, issue 2, pp. 705-714, 2021 Apr 30. PMCID: PMC8106500  PMID: 33843974

2020

Mincham, K. T., A. C. Jones, M. Bodinier, N. M. Scott, J-F. Lauzon-Joset, P. A. Stumbles, A. Bosco, P. G. Holt, and D. H. Strickland, "Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming.", Front Immunol, vol. 11, pp. 601494, 2020. PMCID: PMC7793790  PMID: 33424847
Guo, J., Y. Song, A. Saiganesh, B. J. Hales, A. Bosco, P. N. Le Souëf, and G. Zhang, "Toll-like receptor signalling has inverted U-shaped response over time with the Western environment.", Allergy, vol. 75, issue 10, pp. 2665-2667, 2020 Oct. PMID: 32171026
Read, J. F., and A. Bosco, "Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children.", Int J Mol Sci, vol. 21, issue 17, 2020 Sep 02. PMCID: PMC7503410  PMID: 32887352
Jones, A. C., D. Anderson, N. M. Troy, D. Mallon, R. Hartmann, M. Serralha, B. Holt, A. Bosco, and P. G. Holt, "Rewiring of gene networks underlying mite allergen-induced CD4 + Th-cell responses during immunotherapy.", Allergy, vol. 75, issue 9, pp. 2330-2341, 2020 Sep. PMID: 32181882
Anderson, D., A. C. Jones, C. M. Gaido, K. W. Carter, I. A. Laing, A. Bosco, W. R. Thomas, and B. J. Hales, "Differential Gene Expression of Lymphocytes Stimulated with Rhinovirus A and C in Children with Asthma.", Am J Respir Crit Care Med, vol. 202, issue 2, pp. 202-209, 2020 Jul 15. PMID: 32142615
Kicic, A., E. de Jong, K-M. Ling, K. Nichol, D. Anderson, P. A. B. Wark, D. A. Knight, A. Bosco, and S. M. Stick, "Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium.", J Allergy Clin Immunol, vol. 145, issue 6, pp. 1562-1573, 2020 Jun. PMID: 32113981
Veerati, P. Chander, N. M. Troy, A. T. Reid, N. Fung Li, K. S. Nichol, P. Kaur, S. Maltby, P. A. B. Wark, D. A. Knight, A. Bosco, et al., "Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD.", Front Immunol, vol. 11, pp. 974, 2020. PMCID: PMC7243842  PMID: 32499788
Zemek, R. M., V. S. Fear, C. Forbes, E. de Jong, T. H. Casey, L. Boon, T. Lassmann, A. Bosco, M. J. Millward, A. K. Nowak, et al., "Bilateral murine tumor models for characterizing the response to immune checkpoint blockade.", Nat Protoc, vol. 15, issue 5, pp. 1628-1648, 2020 May. PMCID: 3544539  PMID: 32238953

2019

Jones, A. C., D. Anderson, S. Galbraith, E. Fantino, D. Gutierrez Cardenas, J. F. Read, M. Serralha, B. J. Holt, D. H. Strickland, P. D. Sly, et al., "Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles.", J Allergy Clin Immunol, vol. 144, issue 5, pp. 1411-1413, 2019 Nov. PMID: 31437489
Leffler, J., J. F. Read, A. C. Jones, D. Mok, E. M. Hollams, I. A. Laing, P. N. Le Souëf, P. D. Sly, M. M. H. Kusel, N. H. de Klerk, et al., "Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children.", Pediatr Allergy Immunol, vol. 30, issue 6, pp. 646-653, 2019 Sep. PMID: 30985951
Mehr, S., E. Lee, P. Hsu, D. Anderson, E. de Jong, A. Bosco, and D. E. Campbell, "Innate immune activation occurs in acute food protein-induced enterocolitis syndrome reactions.", J Allergy Clin Immunol, vol. 144, issue 2, pp. 600-602.e2, 2019 Aug. PMID: 31059725
Zemek, R. M., E. de Jong, W. Loong Chin, I. S. Schuster, V. S. Fear, T. H. Casey, C. Forbes, S. J. Dart, C. Leslie, A. Zaitouny, et al., "Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment.", Sci Transl Med, vol. 11, issue 501, 2019 Jul 17. PMID: 31316010
Jones, A. C., D. Anderson, S. Galbraith, E. Fantino, D. Gutierrez Cardenas, J. F. Read, M. Serralha, B. J. Holt, D. H. Strickland, P. D. Sly, et al., "Personalized Transcriptomics Reveals Heterogeneous Immunophenotypes in Children with Viral Bronchiolitis.", Am J Respir Crit Care Med, vol. 199, issue 12, pp. 1537-1549, 2019 Jun 15. PMID: 30562046
Khoo, S-K., J. Read, K. Franks, G. Zhang, J. Bizzintino, L. Coleman, C. McCrae, L. Öberg, N. M. Troy, F. Prastanti, et al., "Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing.", J Immunol, vol. 202, issue 6, pp. 1845-1858, 2019 Mar 15. PMID: 30745463
Corley, S. M., N. M. Troy, A. Bosco, and M. R. Wilkins, "QuantSeq. 3' Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis.", Sci Rep, vol. 9, issue 1, pp. 18895, 2019 Dec 11. PMCID: PMC6906367  PMID: 31827207

2018

Jones, A. C., N. M. Troy, E. White, E. M. Hollams, A. M. Gout, K-M. Ling, A. Kicic, S. M. Stick, P. D. Sly, P. G. Holt, et al., "Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics.", Sci Rep, vol. 8, issue 1, pp. 1511, 2018 Jan 24. PMCID: PMC5784090  PMID: 29367592
Wylie, B., J. Read, A. C. Buzzai, T. Wagner, N. Troy, G. Syn, S. R. Stone, B. Foley, A. Bosco, M. N. Cruickshank, et al., "CD8XCR1 Dendritic Cells Express High Levels of Toll-Like Receptor 5 and a Unique Complement of Endocytic Receptors.", Front Immunol, vol. 9, pp. 2990, 2018. PMCID: PMC6343586  PMID: 30700986
Hurgobin, B., E. de Jong, and A. Bosco, "Insights into respiratory disease through bioinformatics.", Respirology, vol. 23, issue 12, pp. 1117-1126, 2018 Dec. PMID: 30218470
Leffler, J., A. C. Jones, E. M. Hollams, F. Prastanti, P. N. Le Souëf, P. G. Holt, A. Bosco, I. A. Laing, and D. H. Strickland, "Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations.", J Allergy Clin Immunol, vol. 142, issue 5, pp. 1639-1641.e5, 2018 Nov. PMID: 30036597
Lauzon-Joset, J-F., A. C. Jones, K. T. Mincham, J. A. Thomas, L. A. Rosenthal, A. Bosco, P. G. Holt, and D. H. Strickland, "Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies.", Front Immunol, vol. 9, pp. 1805, 2018. PMCID: PMC6099265  PMID: 30150981
de Jong, E., and A. Bosco, "Dissecting Asthma Transcriptomics: Does Site Matter?", Am J Respir Cell Mol Biol, vol. 58, issue 2, pp. 144-146, 2018 Feb. PMID: 29388830

2017

Gardeux, V., J. Berghout, I. Achour, G. A Schissler, Q. Li, C. Kenost, J. Li, Y. Shang, A. Bosco, D. Saner, et al., "A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations.", J Am Med Inform Assoc, vol. 24, issue 6, pp. 1116-1126, 2017 Nov 01. PMCID: PMC6080688  PMID: 29016970
Xi, Y., N. M. Troy, D. Anderson, O. M. Pena, J. P. Lynch, S. Phipps, A. Bosco, and J. W. Upham, "Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16.", Front Immunol, vol. 8, pp. 1351, 2017. PMCID: PMC5660993  PMID: 29118754
Tarique, A. A., P. D. Sly, P. G. Holt, A. Bosco, R. S. Ware, J. Logan, S. C. Bell, C. E. Wainwright, and E. Fantino, "CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis.", J Cyst Fibros, vol. 16, issue 4, pp. 475-482, 2017 Jul. PMID: 28428011
Jones, A. C., and A. Bosco, "Using Network Analysis to Understand Severe Asthma Phenotypes.", Am J Respir Crit Care Med, vol. 195, issue 11, pp. 1409-1411, 2017 Jun 01. PMID: 28569573
Scott, N. M., J. F. Lauzon-Joset, A. C. Jones, K. T. Mincham, N. M. Troy, J. Leffler, M. Serralha, S. L. Prescott, S. A. Robertson, C. Pasquali, et al., "Protection against maternal infection-associated fetal growth restriction: proof-of-concept with a microbial-derived immunomodulator.", Mucosal Immunol, vol. 10, issue 3, pp. 789-801, 2017 May. PMID: 27759021
W Lesterhuis, J., A. Bosco, M. J. Millward, M. Small, A. K. Nowak, and R. A. Lake, "Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity.", Nat Rev Drug Discov, vol. 16, issue 4, pp. 264-272, 2017 Apr. PMID: 28057932

2016

Coleman, L., I. A. Laing, and A. Bosco, "Rhinovirus-induced asthma exacerbations and risk populations.", Curr Opin Allergy Clin Immunol, vol. 16, issue 2, pp. 179-85, 2016 Apr. PMID: 26836624
Troy, N. M., E. M. Hollams, P. G. Holt, and A. Bosco, "Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.", BMC Med Genomics, vol. 9, pp. 9, 2016 Feb 27. PMCID: PMC4769846  PMID: 26922672
Bosco, A., S. Wiehler, and D. Proud, "Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection.", BMC Genomics, vol. 17, pp. 76, 2016 Jan 25. PMCID: PMC4727386  PMID: 26810609
Troy, N. M., and A. Bosco, "Respiratory viral infections and host responses; insights from genomics.", Respir Res, vol. 17, issue 1, pp. 156, 2016 Nov 21. PMCID: PMC5117516  PMID: 27871304
Looi, K., N. M. Troy, L. W. Garratt, T. Iosifidis, A. Bosco, A. G. Buckley, K-M. Ling, K. M. Martinovich, E. Kicic-Starcevich, N. C. Shaw, et al., "Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.", Exp Lung Res, vol. 42, issue 7, pp. 380-395, 2016. PMID: 27726456
Foong, R. E., A. Bosco, N. M. Troy, S. Gorman, P. H. Hart, A. Kicic, and G. R. Zosky, "Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways disease.", Am J Physiol Lung Cell Mol Physiol, vol. 311, issue 3, pp. L653-63, 2016 Sep 01. PMID: 27496895
Eguíluz-Gracia, I., A. Bosco, R. Dollner, G. Reinholt Melum, M. H. Lexberg, A. C. Jones, S. Ahmed Dheyauldeen, P. G. Holt, E. S. Bækkevold, and F. Lars Jahnsen, "Rapid recruitment of CD14(+) monocytes in experimentally induced allergic rhinitis in human subjects.", J Allergy Clin Immunol, vol. 137, issue 6, pp. 1872-1881.e12, 2016 Jun. PMID: 26851967

2015

Foong, R. E., A. Bosco, A. C. Jones, A. Gout, S. Gorman, P. H. Hart, and G. R. Zosky, "The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function.", Am J Respir Cell Mol Biol, vol. 53, issue 5, pp. 664-75, 2015 Nov. PMID: 25867172
W Lesterhuis, J., C. Rinaldi, A. Jones, E. N. Rozali, I. M. Dick, A. Khong, L. Boon, B. W. Robinson, A. K. Nowak, A. Bosco, et al., "Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations.", Sci Rep, vol. 5, pp. 12298, 2015 Jul 21. PMCID: PMC4508665  PMID: 26193793
Gardeux, V., A. Bosco, J. Li, M. J. Halonen, D. Jackson, F. D. Martinez, and Y. A. Lussier, "Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes.", J Biomed Inform, vol. 55, pp. 94-103, 2015 Jun. PMCID: PMC4951181  PMID: 25797143

2014

Stone, S. F., A. Bosco, A. Jones, C. L. Cotterell, P. E. van Eeden, G. Arendts, D. M. Fatovich, and S. G. A. Brown, "Genomic responses during acute human anaphylaxis are characterized by upregulation of innate inflammatory gene networks.", PLoS One, vol. 9, issue 7, pp. e101409, 2014. PMCID: PMC4077795  PMID: 24983946
W Lesterhuis, J., A. Bosco, and R. A. Lake, "Comment on "drug discovery: turning the titanic".", Sci Transl Med, vol. 6, issue 229, pp. 229le2, 2014 Mar 26. PMID: 24670682
Agdestein, A., A. Jones, A. Flatberg, T. B. Johansen, I. Austrheim Heffernan, B. Djønne, A. Bosco, and I. Olsen, "Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection.", BMC Genomics, vol. 15, pp. 58, 2014 Jan 23. PMCID: PMC3906092  PMID: 24450835

2013

Ramsey, K. A., A. Bosco, K. L. McKenna, K. W. Carter, J. G. Elliot, L. J. Berry, P. D. Sly, A. N. Larcombe, and G. R. Zosky, "In utero exposure to arsenic alters lung development and genes related to immune and mucociliary function in mice.", Environ Health Perspect, vol. 121, issue 2, pp. 244-50, 2013 Feb. PMCID: PMC3569690  PMID: 23221970

2012

Rate, A., A. Bosco, K. L. McKenna, P. G. Holt, and J. W. Upham, "Airway epithelial cells condition dendritic cells to express multiple immune surveillance genes.", PLoS One, vol. 7, issue 9, pp. e44941, 2012. PMCID: PMC3439377  PMID: 22984588
White, O. J., K. L. McKenna, A. Bosco, A. H. J. van den Biggelaar, P. Richmond, and P. G. Holt, "A genomics-based approach to assessment of vaccine safety and immunogenicity in children.", Vaccine, vol. 30, issue 10, pp. 1865-74, 2012 Feb 27. PMID: 22230586
Martino, D. J., A. Bosco, K. L. McKenna, E. Hollams, D. Mok, P. G. Holt, and S. L. Prescott, "T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergy.", Allergy, vol. 67, issue 2, pp. 191-200, 2012 Feb. PMID: 22077487
Bosco, A., S. Ehteshami, S. Panyala, and F. D. Martinez, "Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo.", J Allergy Clin Immunol, vol. 129, issue 1, pp. 88-94, 2012 Jan. PMCID: PMC3246116  PMID: 22112518

2011

van den Biggelaar, A. H. J., W. Pomat, A. Bosco, S. Phuanukoonnon, C. J. Devitt, M. A. Nadal-Sims, P. M. Siba, P. C. Richmond, D. Lehmann, and P. G. Holt, "Pneumococcal conjugate vaccination at birth in a high-risk setting: no evidence for neonatal T-cell tolerance.", Vaccine, vol. 29, issue 33, pp. 5414-20, 2011 Jul 26. PMCID: PMC3146700  PMID: 21645573

2010

Bosco, A., S. Ehteshami, D. A. Stern, and F. D. Martinez, "Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction.", Mucosal Immunol, vol. 3, issue 4, pp. 399-409, 2010 Jul. PMCID: PMC2891355  PMID: 20336062
Holt, P. G., J. Rowe, M. Kusel, F. Parsons, E. M. Hollams, A. Bosco, K. McKenna, L. Subrata, N. de Klerk, M. Serralha, et al., "Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study.", J Allergy Clin Immunol, vol. 125, issue 3, pp. 653-9, 659.e1-659.e7, 2010 Mar. PMID: 20226300

2009

Rate, A., J. W. Upham, A. Bosco, K. L. McKenna, and P. G. Holt, "Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease.", J Immunol, vol. 182, issue 1, pp. 72-83, 2009 Jan 01. PMID: 19109137
Yerkovich, S. T., M. Roponen, M. E. Smith, K. McKenna, A. Bosco, L. S. Subrata, E. Mamessier, M. E. Wikström, P. Le Souëf, P. D. Sly, et al., "Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response.", J Allergy Clin Immunol, vol. 123, issue 1, pp. 209-216.e4, 2009 Jan. PMID: 18947863
Holt, P. G., D. H. Strickland, A. Bosco, and F. L. Jahnsen, "Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm.", Adv Immunol, vol. 104, pp. 51-113, 2009. PMID: 20457116
Subrata, L. S., J. Bizzintino, E. Mamessier, A. Bosco, K. L. McKenna, M. E. Wikström, J. Goldblatt, P. D. Sly, B. J. Hales, W. R. Thomas, et al., "Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children.", J Immunol, vol. 183, issue 4, pp. 2793-800, 2009 Aug 15. PMID: 19620293
Bosco, A., K. L. McKenna, M. J. Firth, P. D. Sly, and P. G. Holt, "A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease.", J Immunol, vol. 182, issue 10, pp. 6011-21, 2009 May 15. PMCID: PMC9563009  PMID: 19414752
Zhang, G., J. Rowe, M. Kusel, A. Bosco, K. McKenna, N. de Klerk, P. D. Sly, and P. G. Holt, "Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history.", Am J Respir Crit Care Med, vol. 179, issue 3, pp. 205-11, 2009 Feb 01. PMID: 18996999

2008

Bosco, A., and P. G. Holt, "Genome-wide expression profiling of T-cells in childhood wheeze.", Eur Respir J, vol. 32, issue 5, pp. 1138-40, 2008 Nov. PMID: 18978130

2006

White, G. P., E. M. Hollams, S. T. Yerkovich, A. Bosco, B. J. Holt, M. R. Bassami, M. Kusel, P. D. Sly, and P. G. Holt, "CpG methylation patterns in the IFNgamma promoter in naive T cells: variations during Th1 and Th2 differentiation and between atopics and non-atopics.", Pediatr Allergy Immunol, vol. 17, issue 8, pp. 557-64, 2006 Dec. PMID: 17121582
Bosco, A., K. L. McKenna, C. J. Devitt, M. J. Firth, P. D. Sly, and P. G. Holt, "Identification of novel Th2-associated genes in T memory responses to allergens.", J Immunol, vol. 176, issue 8, pp. 4766-77, 2006 Apr 15. PMID: 16585570

2004

Hales, B. J., A. Bosco, K. L. Mills, L. A. Hazell, R. Loh, P. G. Holt, and W. R. Thomas, "Isoforms of the major peanut allergen Ara h 2: IgE binding in children with peanut allergy.", Int Arch Allergy Immunol, vol. 135, issue 2, pp. 101-7, 2004 Oct. PMID: 15345908

2001

Stumbles, P. A., D. H. Strickland, C. L. Pimm, S. F. Proksch, A. M. Marsh, A. S. McWilliam, A. Bosco, I. Tobagus, J. A. Thomas, S. Napoli, et al., "Regulation of dendritic cell recruitment into resting and inflamed airway epithelium: use of alternative chemokine receptors as a function of inducing stimulus.", J Immunol, vol. 167, issue 1, pp. 228-34, 2001 Jul 01. PMID: 11418653