2010
Weyand, Nathan J, Calton, Christine M, Higashi, Dustin L, Kanack, Kristen J, So, Magdalene. Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection. J Immunol. 2010;184(2):694-701. doi:10.4049/jimmunol.0900522
Doyle, Kristian P, Cekanaviciute, Egle, Mamer, Lauren E, Buckwalter, Marion S. TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. J Neuroinflammation. 2010;7:62. doi:10.1186/1742-2094-7-62
Rao, Rajesh R, Li, Qingsheng, Odunsi, Kunle, Shrikant, Protul A. The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin. Immunity. 2010;32(1):67-78. doi:10.1016/j.immuni.2009.10.010
Vincent, Benjamin G, Young, Ellen F, Buntzman, Adam S, et al. Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice. J Immunol. 2010;184(8):4196-204. doi:10.4049/jimmunol.0903931
Matsuzaki, Junko, Gnjatic, Sacha, Mhawech-Fauceglia, Paulette, et al. Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. Proc Natl Acad Sci U S A. 2010;107(17):7875-80. doi:10.1073/pnas.1003345107
2009
Higashi, Dustin L, Zhang, Gina H, Biais, Nicolas, et al. Influence of type IV pilus retraction on the architecture of the Neisseria gonorrhoeae-infected cell cortex. Microbiology. 2009;155(Pt 12):4084-92. doi:10.1099/mic.0.032656-0
Wilson, Justin E, Katkere, Bhuvana, Drake, James R. Francisella tularensis induces ubiquitin-dependent major histocompatibility complex class II degradation in activated macrophages. Infect Immun. 2009;77(11):4953-65. doi:10.1128/IAI.00844-09
Kleinridders, André, Schenten, Dominik, Könner, A Christine, et al. MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. 2009;10(4):249-59. doi:10.1016/j.cmet.2009.08.013
West, G Alexander, Golshani, Kiarash J, Doyle, Kristian P, et al. A new model of cortical stroke in the rhesus macaque. J Cereb Blood Flow Metab. 2009;29(6):1175-86. doi:10.1038/jcbfm.2009.43
Petrucelli, Alex, Rak, Michael, Grainger, Lora, Goodrum, Felicia. Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus. J Virol. 2009;83(11):5615-29. doi:10.1128/JVI.01989-08
Chen, Wei, Begum, Salma, Opare-Addo, Lynn, et al. Promotion of beta-cell differentiation in pancreatic precursor cells by adult islet cells. Endocrinology. 2009;150(2):570-9. doi:10.1210/en.2008-1009
Bosco, Anthony, McKenna, Kathy L, Firth, Martin J, Sly, Peter D, Holt, Patrick G. A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease. J Immunol. 2009;182(10):6011-21. doi:10.4049/jimmunol.0804125
Rate, Angela, Upham, John W, Bosco, Anthony, McKenna, Kathy L, Holt, Patrick G. Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. J Immunol. 2009;182(1):72-83. doi:10.4049/jimmunol.182.1.72
Yerkovich, Stephanie T, Roponen, Marjut, Smith, Miranda E, et al. Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response. J Allergy Clin Immunol. 2009;123(1):209-216.e4. doi:10.1016/j.jaci.2008.09.009
Wu, Hsin-Jung, Bondada, Subbarao. CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function. J Clin Immunol. 2009;29(1):12-21. doi:10.1007/s10875-008-9264-6
Wellensiek, Brian P, Ramakrishnan, Rajesh, Sundaravaradan, Vasudha, Mehta, Roshni, Harris, David T, Ahmad, Nafees. Differential HIV-1 integration targets more actively transcribed host genes in neonatal than adult blood mononuclear cells. Virology. 2009;385(1):28-38. doi:10.1016/j.virol.2008.10.052
Qian, Feng, Villella, Jeannine, Wallace, Paul K, et al. Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer. Cancer Res. 2009;69(13):5498-504. doi:10.1158/0008-5472.CAN-08-2106
Jacobs, Jonathan P, Wu, Hsin-Jung, Benoist, Christophe, Mathis, Diane. IL-17-producing T cells can augment autoantibody-induced arthritis. Proc Natl Acad Sci U S A. 2009;106(51):21789-94. doi:10.1073/pnas.0912152106
Subrata, Lily S, Bizzintino, Joelene, Mamessier, Emilie, et al. Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children. J Immunol. 2009;183(4):2793-800. doi:10.4049/jimmunol.0900695
Zhang, Guicheng, Rowe, Julie, Kusel, Merci, et al. Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history. Am J Respir Crit Care Med. 2009;179(3):205-11. doi:10.1164/rccm.200803-438OC
Holt, Patrick G, Strickland, Deborah H, Bosco, Anthony, Jahnsen, Frode L. Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm. Adv Immunol. 2009;104:51-113. doi:10.1016/S0065-2776(08)04003-0
Schenten, Dominik, Kracker, Sven, Esposito, Gloria, et al. Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability. J Exp Med. 2009;206(2):477-90. doi:10.1084/jem.20080669
Purdy, John G, Flanagan, John M, Ropson, Ira J, Craven, Rebecca C. Retroviral capsid assembly: a role for the CA dimer in initiation. J Mol Biol. 2009;389(2):438-51. doi:10.1016/j.jmb.2009.04.006
Das, Jyoti, Ren, Guangwen, Zhang, Liying, et al. Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation. J Exp Med. 2009;206(11):2407-16. doi:10.1084/jem.20082286
Campos, Samuel K, Ozbun, Michelle A. Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes. PLoS One. 2009;4(2):e4463. doi:10.1371/journal.pone.0004463
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