Publications

2021

Bates, N. A., A. Li, T. Fan, M. P. Cutcliffe, C. B. Dagenet, K. C. Sleiman, H. Ma, S. Tahsin, C. S. Garrett, J. Altemus, et al., "Gut Commensal Segmented Filamentous Bacteria Fine-Tune T Follicular Regulatory Cells to Modify the Severity of Systemic Autoimmune Arthritis.", J Immunol, vol. 206, issue 5, pp. 941-952, 2021 Mar 01. PMID: 33462137
Zaiss, M. M., H-J. Joyce Wu, D. Mauro, G. Schett, and F. Ciccia, "The gut-joint axis in rheumatoid arthritis.", Nat Rev Rheumatol, vol. 17, issue 4, pp. 224-237, 2021 Apr. PMID: 33674813
Wu, H-J. Joyce, "Methotrexate works remotely, from the gut.", Cell Host Microbe, vol. 29, issue 3, pp. 325-326, 2021 03 10. PMID: 33705703

2019

Sprouse, M. L., N. A. Bates, K. M. Felix, and H-J. Joyce Wu, "Impact of gut microbiota on gut-distal autoimmunity: a focus on T cells.", Immunology, vol. 156, issue 4, pp. 305-318, 2019 Apr. PMCID: PMC6418419  PMID: 30560993
Felix, K. M., F. Teng, N. A. Bates, H. Ma, I. A. Jaimez, K. C. Sleiman, N. L. Tran, and H-J. Joyce Wu, "P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response.", Front Immunol, vol. 10, pp. 411, 2019. PMCID: PMC6436202  PMID: 30949163

2018

Felix, K. M., I. A. Jaimez, T-V. V. Nguyen, H. Ma, W. A. Raslan, C. N. Klinger, K. P. Doyle, and H-J. J. Wu, "Gut Microbiota Contributes to Resistance Against Pneumococcal Pneumonia in Immunodeficient Rag Mice.", Front Cell Infect Microbiol, vol. 8, pp. 118, 2018. PMCID: PMC5932343  PMID: 29755958

2017

Viladomiu, M., C. Kivolowitz, A. Abdulhamid, B. Dogan, D. Victorio, J. G. Castellanos, V. Woo, F. Teng, N. L. Tran, A. Sczesnak, et al., "IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.", Sci Transl Med, vol. 9, issue 376, 2017 Feb 08. PMID: 28179509
Naskar, D., F. Teng, K. M. Felix, P. C Bradley, and H-J. Joyce Wu, "Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses.", J Immunol, vol. 198, issue 5, pp. 1855-1864, 2017 Mar 01. PMCID: PMC5324833  PMID: 28130500
C Bradley, P., F. Teng, K. M. Felix, T. Sano, D. Naskar, K. E. Block, H. Huang, K. S. Knox, D. R. Littman, and H-J. Joyce Wu, "Segmented Filamentous Bacteria Provoke Lung Autoimmunity by Inducing Gut-Lung Axis Th17 Cells Expressing Dual TCRs.", Cell Host Microbe, vol. 22, issue 5, pp. 697-704.e4, 2017 11 08. PMCID: PMC5749641  PMID: 29120746
Felix, K. M., S. Tahsin, and H-J. Joyce Wu, "Host-microbiota interplay in mediating immune disorders.", Ann N Y Acad Sci, 2017 Oct 06. PMCID: PMC5889363  PMID: 28984367

2016

Teng, F., C. N. Klinger, K. M. Felix, P. C Bradley, E. Wu, N. L. Tran, Y. Umesaki, and H-J. Joyce Wu, "Gut Microbiota Drive Autoimmune Arthritis by Promoting Differentiation and Migration of Peyer's Patch T Follicular Helper Cells.", Immunity, vol. 44, issue 4, pp. 875-88, 2016 Apr 19. PMID: 27096318
Tan, T. Guan, E. Sefik, N. Geva-Zatorsky, L. Kua, D. Naskar, F. Teng, L. Pasman, A. Ortiz-Lopez, R. Jupp, H-J. Joyce Wu, et al., "Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice.", Proc Natl Acad Sci U S A, vol. 113, issue 50, pp. E8141-E8150, 2016 Dec 13. PMCID: PMC5167147  PMID: 27911839

2012

Wu, H-J., and E. Wu, "The role of gut microbiota in immune homeostasis and autoimmunity.", Gut Microbes, vol. 3, issue 1, pp. 4-14, 2012 Jan-Feb. PMCID: PMC3337124  PMID: 22356853

2011

Kriegel, M. A., E. Sefik, J. A. Hill, H-J. Wu, C. Benoist, and D. Mathis, "Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice.", Proc Natl Acad Sci U S A, vol. 108, issue 28, pp. 11548-53, 2011 Jul 12. PMCID: PMC3136249  PMID: 21709219

2010

Wu, H-J., I. I. Ivanov, J. Darce, K. Hattori, T. Shima, Y. Umesaki, D. R. Littman, C. Benoist, and D. Mathis, "Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells.", Immunity, vol. 32, issue 6, pp. 815-27, 2010 Jun 25. PMCID: PMC2904693  PMID: 20620945

2009

Jacobs, J. P., H-J. Wu, C. Benoist, and D. Mathis, "IL-17-producing T cells can augment autoantibody-induced arthritis.", Proc Natl Acad Sci U S A, vol. 106, issue 51, pp. 21789-94, 2009 Dec 22. PMCID: PMC2799826  PMID: 19955422
Wu, H-J., and S. Bondada, "CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function.", J Clin Immunol, vol. 29, issue 1, pp. 12-21, 2009 Jan. PMID: 19067131

2007

Wu, H-J., H. Sawaya, B. Binstadt, M. Brickelmaier, A. Blasius, L. Gorelik, U. Mahmood, R. Weissleder, J. Carulli, C. Benoist, et al., "Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk.", J Exp Med, vol. 204, issue 8, pp. 1911-22, 2007 Aug 6. PMCID: PMC2118664  PMID: 17646407

2002

Wu, H-J., and S. Bondada, "Positive and negative roles of CD72 in B cell function.", Immunol Res, vol. 25, issue 2, pp. 155-66, 2002. PMID: 11999169

2001

Wu, H. J., C. Venkataraman, S. Estus, C. Dong, R. J. Davis, R. A. Flavell, and S. Bondada, "Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation.", J Immunol, vol. 167, issue 3, pp. 1263-73, 2001 Aug 1. PMID: 11466342