Publications

2023

Ihedioha, O. C., A. Sivakoses, S. M. Beverley, D. McMahon-Pratt, and A. L. M. Bothwell, "derived lipophosphoglycan influences the host's early immune response by inducing platelet activation and DKK1 production via TLR1/2.", Front Immunol, vol. 14, pp. 1257046, 2023. PMCID: PMC10598878  PMID: 37885890

2021

Park, M. Hee, J. Hun Shin, A. L. M. Bothwell, and W-J. Chae, "Dickkopf proteins in pathological inflammatory diseases.", J Leukoc Biol, 2021 Dec 10. PMID: 34890067
van den Pol, A. N., X. Zhang, S. E. Maher, and A. L. M. Bothwell, "Immune cells enhance Zika virus-mediated neurologic dysfunction in brain of mice with humanized immune systems.", Dev Neurobiol, vol. 81, issue 4, pp. 389-399, 2021 May. PMID: 33811750
Paluri, S. L., M. Burak, A. G. Senejani, M. Levinson, T. Rahim, K. Clairmont, M. Kashgarian, I. Alvarado-Cruz, R. Meas, M. Cardó-Vila, et al., "DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model.", DNA Repair (Amst), vol. 105, pp. 103152, 2021 Sep. PMID: 34186496
Shin, J. Hun, J. Jeong, S. E. Maher, H-W. Lee, J. Lim, and A. L. M. Bothwell, "Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis.", Proc Natl Acad Sci U S A, vol. 118, issue 48, 2021 Nov 30. PMCID: PMC8640789  PMID: 34819374
Shin, J. Hun, J. Jeong, J. Choi, J. Lim, R. K. Dinesh, J. Braverman, J. Young Hong, S. E. Maher, M. C. Amezcua Vesely, WJ. Kim, et al., "Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1.", iScience, vol. 24, issue 5, pp. 102411, 2021 May 21. PMCID: PMC8099562  PMID: 33997693

2019

Jayakumar, A., and A. L. M. Bothwell, "RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors.", Cancer Res, vol. 79, issue 7, pp. 1587-1599, 2019 04 01. PMCID: PMC7395226  PMID: 30786994
Chae, W-J., and A. L. M. Bothwell, "Dickkopf1: An immunomodulatory ligand and Wnt antagonist in pathological inflammation.", Differentiation, vol. 108, pp. 33-39, 2019 Jul - Aug. PMCID: PMC6982462  PMID: 31221431
Jayakumar, A., and A. L. M. Bothwell, "Functional Diversity of Myeloid-Derived Suppressor Cells: The Multitasking Hydra of Cancer.", J Immunol, vol. 203, issue 5, pp. 1095-1103, 2019 09 01. PMCID: PMC6703177  PMID: 31427398

2018

Ahn, S. S., Y. Park, D. D. Lee, A. L. M. Bothwell, S. M. Jung, J. J. Song, Y-B. Park, and S-W. Lee, "Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein can reflect systemic lupus erythematosus activity.", Lupus, vol. 27, issue 5, pp. 771-779, 2018 Apr. PMID: 29233037
Chae, W-J., and A. L. M. Bothwell, "Canonical and Non-Canonical Wnt Signaling in Immune Cells.", Trends Immunol, vol. 39, issue 10, pp. 830-847, 2018 10. PMCID: PMC7367500  PMID: 30213499
Lim, S., N. C. Kirkiles-Smith, J. S. Pober, A. L. M. Bothwell, and J-M. Choi, "Regulation of human T cell responses by dNP2-ctCTLA-4 inhibits human skin and microvessel graft rejection.", Biomaterials, vol. 183, pp. 128-138, 2018 11. PMCID: PMC6141312  PMID: 30165256
Chae, W-J., and A. L. M. Bothwell, "Therapeutic Potential of Gene-Modified Regulatory T Cells: From Bench to Bedside.", Front Immunol, vol. 9, pp. 303, 2018. PMCID: PMC5820299  PMID: 29503652
Xiao, Q., J. Wu, W-J. Wang, S. Chen, Y. Zheng, X. Yu, K. Meeth, M. Sahraei, A. L. M. Bothwell, L. Chen, et al., "DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.", Nat Med, vol. 24, issue 3, pp. 262-270, 2018 03. PMCID: PMC5840007  PMID: 29431745
Moon, J-S., C. Hee Mun, J-H. Kim, J-Y. Cho, S-D. Park, T-Y. Park, J-S. Shin, C-C. Ho, Y-B. Park, S. Ghosh, et al., "Intranuclear delivery of the transcription modulation domain of Tbet-improved lupus nephritis in (NZB/NZW) F1 lupus-prone mice.", Kidney Int, vol. 93, issue 5, pp. 1118-1130, 2018 05. PMID: 29409726

2017

Jayakumar, A., and A. L. M. Bothwell, "Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response.", Neoplasia, vol. 19, issue 8, pp. 595-605, 2017 Aug. PMCID: PMC5487300  PMID: 28654863
Chae, W-J., J-H. Park, O. Henegariu, S. Yilmaz, L. Hao, and A. L. M. Bothwell, "Membrane-bound Dickkopf-1 in Foxp3 regulatory T cells suppresses T-cell-mediated autoimmune colitis.", Immunology, vol. 152, issue 2, pp. 265-275, 2017 10. PMCID: PMC5588763  PMID: 28556921

2016

Chae, W-J., A. K. Ehrlich, P. Y. Chan, A. M. Teixeira, O. Henegariu, L. Hao, J. Hun Shin, J-H. Park, W. Ho Tang, S-T. Kim, et al., "The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.", Immunity, vol. 44, issue 2, pp. 246-58, 2016 Feb 16. PMCID: PMC4758884  PMID: 26872695
Abrahimi, P., L. Qin, W. G. Chang, A. L. M. Bothwell, G. Tellides, M. W Saltzman, and J. S. Pober, "Blocking MHC class II on human endothelium mitigates acute rejection.", JCI Insight, vol. 1, issue 1, 2016. PMCID: PMC4756651  PMID: 26900601
Park, H-J., H-S. Park, J-U. Lee, A. L. M. Bothwell, and J-M. Choi, "Sex-Based Selectivity of PPARγ Regulation in Th1, Th2, and Th17 Differentiation.", Int J Mol Sci, vol. 17, issue 8, 2016 Aug 18. PMCID: PMC5000743  PMID: 27548145
Park, H-J., H-S. Park, J-U. Lee, A. L. M. Bothwell, and J-M. Choi, "Gender-specific differences in PPARγ regulation of follicular helper T cell responses with estrogen.", Sci Rep, vol. 6, pp. 28495, 2016 06 23. PMCID: PMC4917844  PMID: 27335315
Chae, W-J., and A. L. M. Bothwell, "Snapshots of CD4 T cell plasticity in the pathogenesis of allergic asthma.", J Thorac Dis, vol. 8, issue 9, pp. E1010-E1012, 2016 Sep. PMCID: PMC5059289  PMID: 27747048

2015

Chae, W-J., and A. L. M. Bothwell, "Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A.", J Immunol Res, vol. 2015, pp. 860106, 2015. PMCID: PMC4469837  PMID: 26146642
Lim, S., W-J. Kim, Y-H. Kim, S. Lee, J-H. Koo, J-A. Lee, H. Yoon, D-H. Kim, H-J. Park, H-M. Kim, et al., "dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.", Nat Commun, vol. 6, pp. 8244, 2015 Sep 15. PMCID: PMC4579786  PMID: 26372309

2014

Park, J-H., J. Seung Ko, Y. Shin, J. Young Cho, H-ah. Oh, A. L. M. Bothwell, A. M. Bothwell, and S-K. Lee, "Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells.", Biochem Biophys Res Commun, vol. 451, issue 1, pp. 1-7, 2014 Aug 15. PMID: 25044110
Ehrlich, A., T. Moreno Castilho, K. Goldsmith-Pestana, W-J. Chae, A. L. M. Bothwell, T. Sparwasser, and D. McMahon-Pratt, "The immunotherapeutic role of regulatory T cells in Leishmania (Viannia) panamensis infection.", J Immunol, vol. 193, issue 6, pp. 2961-70, 2014 Sep 15. PMCID: PMC4170189  PMID: 25098291
Senejani, A. G., Y. Liu, D. Kidane, S. E. Maher, C. J. Zeiss, H-J. Park, M. Kashgarian, J. M. McNiff, D. Zelterman, A. L. M. Bothwell, et al., "Mutation of POLB causes lupus in mice.", Cell Rep, vol. 6, issue 1, pp. 1-8, 2014 Jan 16. PMCID: PMC3916967  PMID: 24388753
Milam, A. A. Viehmann, S. E. Maher, J. A. Gibson, J. Lebastchi, L. Wen, N. H. Ruddle, K. C. Herold, and A. L. M. Bothwell, "A humanized mouse model of autoimmune insulitis.", Diabetes, vol. 63, issue 5, pp. 1712-24, 2014 May. PMCID: PMC3994947  PMID: 24478396
Park, T-Y., S-D. Park, J-Y. Cho, J-S. Moon, N-Y. Kim, K. Park, R. Hyun Seong, S-W. Lee, T. Morio, A. L. M. Bothwell, et al., "RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.", Proc Natl Acad Sci U S A, vol. 111, issue 52, pp. 18673-8, 2014 Dec 30. PMCID: PMC4284575  PMID: 25527718
Park, H-J., D-H. Kim, J-Y. Choi, W-J. Kim, J. Yun Kim, A. G. Senejani, S. Seok Hwang, L. Kyun Kim, Z. Tobiasova, G. Ryol Lee, et al., "PPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation.", PLoS One, vol. 9, issue 6, pp. e99127, 2014. PMCID: PMC4055678  PMID: 24921943
Kidane, D., W. Jin Chae, J. Czochor, K. A. Eckert, P. M. Glazer, A. L. M. Bothwell, and J. B. Sweasy, "Interplay between DNA repair and inflammation, and the link to cancer.", Crit Rev Biochem Mol Biol, vol. 49, issue 2, pp. 116-39, 2014 Mar-Apr. PMCID: PMC4300235  PMID: 24410153

2013

Dukhande, V. V., I. Kawikova, A. L. M. Bothwell, and J. C. K. Lai, "Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.", Apoptosis, vol. 18, issue 6, pp. 702-12, 2013 Jun. PMCID: PMC3645366  PMID: 23494481
Kobsa, S., N. J. Kristofik, A. J. Sawyer, A. L. M. Bothwell, T. R. Kyriakides, and M. W Saltzman, "An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds.", Biomaterials, vol. 34, issue 15, pp. 3891-901, 2013 May. PMCID: PMC3625647  PMID: 23453058

2012

Yi, T., B. Fogal, Z. Hao, Z. Tobiasova, C. Wang, D. A. Rao, R. S. Al-Lamki, N. C. Kirkiles-Smith, S. Kulkarni, J. R. Bradley, et al., "Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model.", Arterioscler Thromb Vasc Biol, vol. 32, issue 2, pp. 353-60, 2012 Feb. PMCID: PMC3262100  PMID: 22053072
Choi, J-M., and A. L. M. Bothwell, "The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases.", Mol Cells, vol. 33, issue 3, pp. 217-22, 2012 Mar. PMCID: PMC3887706  PMID: 22382683

2011

Tobiasova, Z., L. Zhang, T. Yi, L. Qin, T. D. Manes, S. Kulkarni, M. I. Lorber, F. C. Rodriguez, J-M. Choi, G. Tellides, et al., "Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells.", Circulation, vol. 124, issue 2, pp. 196-205, 2011 Jul 12. PMCID: PMC3347886  PMID: 21690493
Chae, W-J., and A. L. M. Bothwell, "IL-17F deficiency inhibits small intestinal tumorigenesis in ApcMin/+ mice.", Biochem Biophys Res Commun, vol. 414, issue 1, pp. 31-6, 2011 Oct 14. PMID: 21939640
Tobiasova, Z., K. H. B. van der Lingen, L. Scahill, J. F. Leckman, Y. Zhang, W. Chae, J. T. McCracken, C. J. McDougle, B. Vitiello, E. Tierney, et al., "Risperidone-related improvement of irritability in children with autism is not associated with changes in serum of epidermal growth factor and interleukin-13.", J Child Adolesc Psychopharmacol, vol. 21, issue 6, pp. 555-64, 2011 Dec. PMCID: PMC3279715  PMID: 22070180
Bos-Veneman, N. G. P., R. Olieman, Z. Tobiasova, P. J. Hoekstra, L. Katsovich, A. L. M. Bothwell, J. F. Leckman, and I. Kawikova, "Altered immunoglobulin profiles in children with Tourette syndrome.", Brain Behav Immun, vol. 25, issue 3, pp. 532-8, 2011 Mar. PMCID: PMC3056238  PMID: 21156204

2010

Harding, M. J., C. M. Lepus, T. F. Gibson, B. R. Shepherd, S. A. Gerber, M. Graham, F. X. Paturzo, C. Rahner, J. A. Madri, A. L. M. Bothwell, et al., "An implantable vascularized protein gel construct that supports human fetal hepatoblast survival and infection by hepatitis C virus in mice.", PLoS One, vol. 5, issue 4, pp. e9987, 2010 Apr 01. PMCID: PMC2848675  PMID: 20376322
Kawikova, I., B. P. X. Grady, Z. Tobiasova, Y. Zhang, A. Vojdani, L. Katsovich, B. J. Richmand, T. Won Park, A. L. M. Bothwell, and J. F. Leckman, "Children with Tourette's syndrome may suffer immunoglobulin A dysgammaglobulinemia: preliminary report.", Biol Psychiatry, vol. 67, issue 7, pp. 679-83, 2010 Apr 01. PMCID: PMC3974615  PMID: 20006327
Chae, W-J., T. F. Gibson, D. Zelterman, L. Hao, O. Henegariu, and A. L. M. Bothwell, "Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis.", Proc Natl Acad Sci U S A, vol. 107, issue 12, pp. 5540-4, 2010 Mar 23. PMCID: PMC2851824  PMID: 20212110
Morer, A., W. Chae, O. Henegariu, A. L. M. Bothwell, J. F. Leckman, and I. Kawikova, "Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases.", Brain Behav Immun, vol. 24, issue 7, pp. 1069-73, 2010 Oct. PMID: 20193755
Choi, J-M., J-H. Shin, M-H. Sohn, M. J. Harding, J-H. Park, Z. Tobiasova, D-Y. Kim, S. E. Maher, W-J. Chae, S-H. Park, et al., "Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.", Proc Natl Acad Sci U S A, vol. 107, issue 43, pp. 18575-80, 2010 Oct 26. PMCID: PMC2972952  PMID: 20937878

2009

Das, J., G. Ren, L. Zhang, A. I. Roberts, X. Zhao, A. L. M. Bothwell, L. Van Kaer, Y. Shi, and G. Das, "Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.", J Exp Med, vol. 206, issue 11, pp. 2407-16, 2009 Oct 26. PMCID: PMC2768861  PMID: 19808254
Chen, W., S. Begum, L. Opare-Addo, J. Garyu, T. F. Gibson, A. L. M. Bothwell, V. E. Papaioannou, and K. C. Herold, "Promotion of beta-cell differentiation in pancreatic precursor cells by adult islet cells.", Endocrinology, vol. 150, issue 2, pp. 570-9, 2009 Feb. PMCID: PMC2646532  PMID: 18845629

2008

Giambra, V., S. Volpi, A. V. Emelyanov, D. Pflugh, A. L. M. Bothwell, P. Norio, Y. Fan, Z. Ju, A. I. Skoultchi, R. R. Hardy, et al., "Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.", Mol Cell Biol, vol. 28, issue 19, pp. 6123-33, 2008 Oct. PMCID: PMC2547000  PMID: 18644860
Yi, T., D. A. Rao, P. C Y Tang, Y. Wang, L. A. Cuchara, A. L. M. Bothwell, C. M. Colangelo, G. Tellides, J. S. Pober, and M. I. Lorber, "Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-gamma production by infiltrating T cells.", Transplantation, vol. 86, issue 5, pp. 719-27, 2008 Sep 15. PMCID: PMC2650813  PMID: 18791454
Bai, Y., U. Ahmad, Y. Wang, J. H. Li, J. C. Choy, R. W. Kim, N. Kirkiles-Smith, S. E. Maher, J. G. Karras, F. C Bennett, et al., "Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation.", J Biol Chem, vol. 283, issue 11, pp. 6832-42, 2008 Mar 14. PMID: 18192275
Choi, J-M., S-H. Kim, J-H. Shin, T. Gibson, B-S. Yoon, D-H. Lee, S-K. Lee, A. L. M. Bothwell, J-S. Lim, and S-K. Lee, "Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis.", Proc Natl Acad Sci U S A, vol. 105, issue 50, pp. 19875-80, 2008 Dec 16. PMCID: PMC2604944  PMID: 19066215

2007

Muthukumarana, P., W-J. Chae, S. Maher, B. R. Rosengard, A. L. M. Bothwell, and S. M. Metcalfe, "Regulatory transplantation tolerance and "stemness": evidence that Foxp3 may play a regulatory role in SOCS-3 gene transcription.", Transplantation, vol. 84, issue 1 Suppl, pp. S6-11, 2007 Jul 15. PMID: 17632414
Kawikova, I., J. F. Leckman, H. Kronig, L. Katsovich, D. E. Bessen, M. Ghebremichael, and A. L. M. Bothwell, "Decreased numbers of regulatory T cells suggest impaired immune tolerance in children with tourette syndrome: a preliminary study.", Biol Psychiatry, vol. 61, issue 3, pp. 273-8, 2007 Feb 01. PMID: 16996487

2006

Isaac, A. Orina, I. Kawikova, A. L. M. Bothwell, C. K. Daniels, and J. C. K. Lai, "Manganese treatment modulates the expression of peroxisome proliferator-activated receptors in astrocytoma and neuroblastoma cells.", Neurochem Res, vol. 31, issue 11, pp. 1305-16, 2006 Nov. PMID: 17053972
Das, G., J. Das, P. Eynott, Y. Zhang, A. L. M. Bothwell, L. Van Kaer, and Y. Shi, "Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases.", J Exp Med, vol. 203, issue 12, pp. 2603-11, 2006 Nov 27. PMCID: PMC2118151  PMID: 17088432
Chae, W-J., O. Henegariu, S-K. Lee, and A. L. M. Bothwell, "The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells.", Proc Natl Acad Sci U S A, vol. 103, issue 25, pp. 9631-6, 2006 Jun 20. PMCID: PMC1480458  PMID: 16769892
Nakayama, Y., P. Stabach, S. E. Maher, M. C. Mahajan, P. Masiar, C. Liao, X. Zhang, Z-jia. Ye, D. Tuck, A. L. M. Bothwell, et al., "A limited number of genes are involved in the differentiation of germinal center B cells.", J Cell Biochem, vol. 99, issue 5, pp. 1308-25, 2006 Dec 01. PMID: 16795035

2005

Horowitz, M. C., A. L. M. Bothwell, D. G. T. Hesslein, D. L. Pflugh, and D. G. Schatz, "B cells and osteoblast and osteoclast development.", Immunol Rev, vol. 208, pp. 141-53, 2005 Dec. PMID: 16313346
Zhang, Z., T. Welte, N. Troiano, S. E. Maher, X-Y. Fu, and A. L. M. Bothwell, "Osteoporosis with increased osteoclastogenesis in hematopoietic cell-specific STAT3-deficient mice.", Biochem Biophys Res Commun, vol. 328, issue 3, pp. 800-7, 2005 Mar 18. PMID: 15694417

2004

Johnson, K., D. L. Pflugh, D. Yu, D. G. T. Hesslein, K-I. Lin, A. L. M. Bothwell, A. Thomas-Tikhonenko, D. G. Schatz, and K. Calame, "B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5.", Nat Immunol, vol. 5, issue 8, pp. 853-61, 2004 Aug. PMCID: PMC1635547  PMID: 15258579
Zheng, L., T. F. Gibson, J. S. Schechner, J. S. Pober, and A. L. M. Bothwell, "Bcl-2 transduction protects human endothelial cell synthetic microvessel grafts from allogeneic T cells in vivo.", J Immunol, vol. 173, issue 5, pp. 3020-6, 2004 Sep 01. PMID: 15322161
Fernandez-Cabezudo, M. J., C. Vijayasarathy, D. L. Pflugh, A. L. M. Bothwell, and B. K. al-Ramadi, "Evidence for a dual pathway of activation in CD43-stimulated Th2 cells: differential requirement for the Lck tyrosine kinase.", Int Immunol, vol. 16, issue 8, pp. 1215-23, 2004 Aug. PMID: 15237112
Torpey, N., S. E. Maher, A. L. M. Bothwell, and J. S. Pober, "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells.", J Biol Chem, vol. 279, issue 25, pp. 26789-96, 2004 Jun 18. PMID: 15087447
Horowitz, M. C., Y. Xi, D. L. Pflugh, D. G. T. Hesslein, D. G. Schatz, J. A. Lorenzo, and A. L. M. Bothwell, "Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors.", J Immunol, vol. 173, issue 11, pp. 6583-91, 2004 Dec 01. PMID: 15557148
Chae, W-J., H-K. Lee, J-H. Han, S-W. Vincent Kim, A. L. M. Bothwell, T. Morio, and S-K. Lee, "Qualitatively differential regulation of T cell activation and apoptosis by T cell receptor zeta chain ITAMs and their tyrosine residues.", Int Immunol, vol. 16, issue 9, pp. 1225-36, 2004 Sep. PMID: 15302845
Geirsson, A., A. L. M. Bothwell, and G. L. Hammond, "Inhibition of alloresponse by a human trophoblast non-coding RNA suppressing class II transactivator promoter III and major histocompatibility class II expression in murine B-lymphocytes.", J Heart Lung Transplant, vol. 23, issue 9, pp. 1077-81, 2004 Sep. PMID: 15454174

2003

Welte, T., S. S. M. Zhang, T. Wang, Z. Zhang, D. G. T. Hesslein, Z. Yin, A. Kano, Y. Iwamoto, E. Li, J. E. Craft, et al., "STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity.", Proc Natl Acad Sci U S A, vol. 100, issue 4, pp. 1879-84, 2003 Feb 18. PMCID: PMC149927  PMID: 12571365
Geirsson, A., R. J. Lynch, I. Paliwal, A. L. M. Bothwell, and G. L. Hammond, "Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes.", Biochem Biophys Res Commun, vol. 301, issue 3, pp. 718-24, 2003 Feb 14. PMID: 12565840
Pober, J. S., A. L. M. Bothwell, M. I. Lorber, J. M. McNiff, J. S. Schechner, and G. Tellides, "Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse.", Springer Semin Immunopathol, vol. 25, issue 2, pp. 167-80, 2003 Sep. PMID: 12955465
Schechner, J. S., S. K. Crane, F. Wang, A. M. Szeglin, G. Tellides, M. I. Lorber, A. L. M. Bothwell, and J. S. Pober, "Engraftment of a vascularized human skin equivalent.", FASEB J, vol. 17, issue 15, pp. 2250-6, 2003 Dec. PMID: 14656987
Hesslein, D. G. T., D. L. Pflugh, D. Chowdhury, A. L. M. Bothwell, R. Sen, and D. G. Schatz, "Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments.", Genes Dev, vol. 17, issue 1, pp. 37-42, 2003 Jan 01. PMCID: PMC195966  PMID: 12514097
Geirsson, A., I. Paliwal, R. J. Lynch, A. L. M. Bothwell, and G. L. Hammond, "Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA.", Transplantation, vol. 76, issue 2, pp. 387-94, 2003 Jul 27. PMID: 12883198
Zhang, Z., E. Jimi, and A. L. M. Bothwell, "Receptor activator of NF-kappa B ligand stimulates recruitment of SHP-1 to the complex containing TNFR-associated factor 6 that regulates osteoclastogenesis.", J Immunol, vol. 171, issue 7, pp. 3620-6, 2003 Oct 01. PMID: 14500659

2002

Kluger, M. S., S. L. Shiao, A. L. M. Bothwell, and J. S. Pober, "Cutting Edge: Internalization of transduced E-selectin by cultured human endothelial cells: comparison of dermal microvascular and umbilical vein cells and identification of a phosphoserine-type di-leucine motif.", J Immunol, vol. 168, issue 5, pp. 2091-5, 2002 Mar 01. PMID: 11859093
Pflugh, D. L., S. E. Maher, and A. L. M. Bothwell, "Ly-6 superfamily members Ly-6A/E, Ly-6C, and Ly-6I recognize two potential ligands expressed by B lymphocytes.", J Immunol, vol. 169, issue 9, pp. 5130-6, 2002 Nov 01. PMID: 12391229
Li, J. Hui, M. S. Kluger, L. A. Madge, L. Zheng, A. L. M. Bothwell, and J. S. Pober, "Interferon-gamma augments CD95(APO-1/Fas) and pro-caspase-8 expression and sensitizes human vascular endothelial cells to CD95-mediated apoptosis.", Am J Pathol, vol. 161, issue 4, pp. 1485-95, 2002 Oct. PMCID: PMC1867313  PMID: 12368221
Zheng, L., L-H. Ben, J. S. Pober, and A. L. M. Bothwell, "Porcine endothelial cells, unlike human endothelial cells, can be killed by human CTL via Fas ligand and cannot be protected by Bcl-2.", J Immunol, vol. 169, issue 12, pp. 6850-5, 2002 Dec 15. PMID: 12471117