Vivian (Thuy-Vi) Nguyen, PhD

Assistant Professor, Neurology
Research Scientist, Immunobiology

Dr. Nguyen earned a PhD from the University of Southern California, in which she investigated neuroprotective mechanisms of sex steroid hormones against Alzheimer’s disease (AD). Dr. Nguyen then trained as a Postdoctoral Fellow at the Buck Institute for Age Research, investigating signaling pathways of neurodegeneration, and how modulating these pathways can influence the AD phenotype. As a Senior Research Scientist at Stanford University, she focused on pre-clinical testing of small molecule peptides for the p75NTR in Alzheimer’s disease (AD) and Down syndrome, with the lead ligand currently in clinical trials for AD. Dr. Nguyen now applies her 10+ years of experience in dementia research by assessing neurodegeneration, immune responses, and behavior in rodent stroke models. 

Recent Publications

2020

Zbesko, J. C., J. Beischel Frye, D. A. Becktel, D. K. Gerardo, J. Stokes, K. Calderon, T-V. V. Nguyen, D. Bhattacharya, and K. P. Doyle, "IgA natural antibodies are produced following T-cell independent B-cell activation following stroke.", Brain Behav Immun, 2020 Sep 18. PMID: 32956832

2018

Zbesko, J. C., T-V. V. Nguyen, T. Yang, J. Beischel Frye, O. Hussain, M. Hayes, A. Chung, A. W Day, K. Stepanovic, M. Krumberger, et al., "Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts.", Neurobiol Dis, vol. 112, pp. 63-78, 2018 Jan 10. PMID: 29331263

2017

Danilo, C. A., E. Constantopoulos, L. A. McKee, H. Chen, J. A. Regan, Y. Lipovka, S. Lahtinen, L. K. Stenman, T-V. V. Nguyen, K. P. Doyle, et al., "Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse.", Benef Microbes, vol. 8, issue 2, pp. 257-269, 2017 Apr 26. PMID: 28409534

2015

Doyle, K. P., L. N. Quach, M. Solé, R. C. Axtell, T-V. V. Nguyen, G. J. Soler-Llavina, S. Jurado, J. Han, L. Steinman, F. M. Longo, et al., "B-lymphocyte-mediated delayed cognitive impairment following stroke.", J Neurosci, vol. 35, issue 5, pp. 2133-45, 2015 Feb 04. PMCID: PMC4315838  PMID: 25653369