Mladen Jergovic, PhD

Assistant Research Professor, Immunobiology

Mladen Jergovic obtained his masters and doctoral degrees at the University of Zagreb, Croatia. In 2015, he joined the Nikolich-Zugich lab as a postdoctoral researcher, where he is currently investigating the molecular mechanisms behind age-dependent vulnerability to infection with intracellular pathogens. Mladen is a postdoc with two small children, so he has no free time or hobbies.

Recent Publications


Jergović, M., M. Watanabe, R. Bhat, C. P. Coplen, S. A. Sonar, R. Wong, Y. Castaneda, L. Davidson, M. Kala, R. C. Wilson, et al., "T-cell cellular stress and reticulocyte signatures, but not loss of naïve T lymphocytes, characterize severe COVID-19 in older adults.", Geroscience, vol. 45, issue 3, pp. 1713-1728, 2023 Jun. PMCID: PMC9838276  PMID: 36633825


Thompson, H. L., M. J. Smithey, J. L. Uhrlaub, I. Jeftić, M. Jergović, S. E. White, N. Currier, A. M. Lang, A. Okoye, B. Park, et al., "Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.", Aging Cell, vol. 18, issue 1, pp. e12865, 2019 Feb. PMCID: PMC6351843  PMID: 30430748
Jergović, M., J. L. Uhrlaub, N. A. Contreras, and J. Nikolich-Zugich, "Do cytomegalovirus-specific memory T cells interfere with new immune responses in lymphoid tissues?", Geroscience, vol. 41, issue 2, pp. 155-163, 2019 Apr. PMID: 31069636
Jergović, M., N. A. Contreras, and J. Nikolich-Zugich, "Impact of CMV upon immune aging: facts and fiction.", Med Microbiol Immunol, 2019 Apr 19. PMID: 31004198
Jergović, M., H. L. Thompson, K. R. Renkema, M. J. Smithey, and J. Nikolich-Zugich, "Defective Transcriptional Programming of Effector CD8 T Cells in Aged Mice Is Cell-Extrinsic and Can Be Corrected by Administration of IL-12 and IL-18.", Front Immunol, vol. 10, pp. 2206, 2019. PMCID: PMC6759569  PMID: 31620129


Mlakar, A. Savić, I. Hojsak, M. Jergović, S. Čimić, and K. Bendelja, "Pediatric Crohn disease is characterized by Th1 in the terminal ileum and Th1/Th17 immune response in the colon.", Eur J Pediatr, vol. 177, issue 4, pp. 611-616, 2018 Apr. PMID: 29397417
Jergović, M., M. J. Smithey, and J. Nikolich-Zugich, "Intrinsic and extrinsic contributors to defective CD8+ T cell responses with aging.", Exp Gerontol, vol. 105, pp. 140-145, 2018 05. PMID: 29337070


Mlakar, A. Savić, I. Hojsak, M. Jergović, V. Vojvoda Parčina, Ž. Babić, B. Troskot, Ž. Mihaljević, and K. Bendelja, "Comparison of Cytokine and Efflux Transporter Expression in Pediatric Versus Adult-onset Ulcerative Colitis.", J Pediatr Gastroenterol Nutr, vol. 64, issue 6, pp. 943-948, 2017 06. PMID: 27622899


Jagušić, M., D. Forčić, M. Brgles, L. Kutle, M. Šantak, M. Jergović, L. Kotarski, K. Bendelja, and B. Halassy, "Stability of Minimum Essential Medium functionality despite L-glutamine decomposition.", Cytotechnology, vol. 68, issue 4, pp. 1171-83, 2016 Aug. PMCID: PMC4960165  PMID: 25904557


Jergović, M., K. Bendelja, A. Savić Mlakar, V. Vojvoda, N. Aberle, T. Jovanovic, S. Rabatić, A. Sabioncello, and A. Vidović, "Circulating levels of hormones, lipids, and immune mediators in post-traumatic stress disorder - a 3-month follow-up study.", Front Psychiatry, vol. 6, pp. 49, 2015. PMCID: PMC4396135  PMID: 25926799