Kristian Doyle, PhD
Associate Professor, Immunobiology
Associate Professor, Neurology
Associate Professor, Psychology
Associate Professor, BIO5 Institute
Associate Professor, Neurosurgery
Associate Professor, Neuroscience-GIDP
Research Scientist, Arizona Center on Aging
Associate Professor, Neurology
Associate Professor, Psychology
Associate Professor, BIO5 Institute
Associate Professor, Neurosurgery
Associate Professor, Neuroscience-GIDP
Research Scientist, Arizona Center on Aging
Kristian Doyle earned his PhD from Oregon Health & Science University in 2007 developing novel therapeutics for stroke in the laboratory of Dr Mary Stenzel-Poore. Dr Doyle then trained as a Postdoctoral Scholar at Stanford University under the mentorship of Dr Marion Buckwalter researching the role of TGFbeta signaling after stroke and developing a model of post stroke dementia. Dr Doyle started as an Assistant Professor at the University of Arizona in 2013. Dr Doyle was awarded an American Federation of Aging Research Fellowship in 2009, an Anita Roberts Young Scientist Scholarship in 2010, and a K99/R00 faculty transition award from the National Institute of Nursing Research in 2012.
Degrees
- PhD: Oregon Health & Science University, 2007
- BS: University of Sussex
Fellowship
- Stanford University
Recent Publications
2024
Becktel, D. A., J. B. Frye, E. H. Le, S. A. Whitman, R. G. Schnellmann, H. W. Morrison, and K. P. Doyle, "Discovering novel plasma biomarkers for ischemic stroke: Lipidomic and metabolomic analyses in an aged mouse model.", J Lipid Res, vol. 65, issue 9, pp. 100614, 2024 Sep.
PMCID: PMC11399596 PMID: 39098585
Bernard, K., J. A. Mota, P. Wene, M. J. Corenblum, J. L. Saez, M. J. Bartlett, L. M Heien, K. P. Doyle, R. Polt, M. Hay, et al., "The angiotensin (1-7) glycopeptide PNA5 improves cognition in a chronic progressive mouse model of Parkinson's disease through modulation of neuroinflammation.", Exp Neurol, vol. 381, pp. 114926, 2024 Nov.
PMID: 39153685
Murphy, D. P., D. C. Dickson, A. N. Fatema, N. G. Carrasco, K. P. Doyle, T. P. Trouard, and H. W. Morrison, "Chronic consequences of ischemic stroke: Profiling brain injury and inflammation in a mouse model with reperfusion.", Physiol Rep, vol. 12, issue 12, pp. e16118, 2024 Jun.
PMCID: PMC11194179 PMID: 38923318
Arizanovska, D., C. A. Dallera, O. O. Folorunso, G. F. Bush, J. B. Frye, K. P. Doyle, J. R. Jagid, H. Wolosker, B. A. Monaco, J. Graciolli Cordeiro, et al., "Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes.", bioRxiv, 2024 Aug 14.
PMCID: PMC11360988 PMID: 39211262
Maiyo, B. K., S. H. Loppi, H. W. Morrison, and K. P. Doyle, "Assessment and Quantification of Foam Cells and Lipid Droplet-Accumulating Microglia in Mouse Brain Tissue Using BODIPY Staining.", Bio Protoc, vol. 14, issue 21, pp. e5107, 2024 Nov 05.
PMCID: PMC11543782 PMID: 39525975
2023
Loppi, S. H., M. A. Tavera-Garcia, N. E. Scholpa, B. K. Maiyo, D. A. Becktel, H. W. Morrison, R. G. Schnellmann, and K. P. Doyle, "Boosting Mitochondrial Biogenesis Diminishes Foam Cell Formation in the Post-Stroke Brain.", Int J Mol Sci, vol. 24, issue 23, 2023 Nov 23.
PMCID: PMC10706318 PMID: 38068955
Zbesko, J. C., J. Stokes, D. A. Becktel, and K. P. Doyle, "Targeting foam cell formation to improve recovery from ischemic stroke.", Neurobiol Dis, vol. 181, pp. 106130, 2023 Jun 01.
PMID: 37068641
Loppi, S. H., M. A. Tavera-Garcia, D. A. Becktel, B. K. Maiyo, K. E. Johnson, T-V. V. Nguyen, R. G. Schnellmann, and K. P. Doyle, "Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke.", J Cereb Blood Flow Metab, vol. 43, issue 7, pp. 1099-1114, 2023 Jul.
PMCID: PMC10291449 PMID: 36772984
2022
Pederson, W. P., L. M. Ellerman, E. C. Sandoval, S. Boitano, J. B. Frye, K. P. Doyle, H. L. Brooks, F. Polverino, and J. G. Ledford, "Development of a Novel Mouse Model of Menopause-associated Asthma.", Am J Respir Cell Mol Biol, vol. 67, issue 5, pp. 605-609, 2022 Nov.
PMCID: PMC9651199 PMID: 36318015
Dwyer, L. J., A. M. Stowe, K. Doyle, P. Popovich, E. Engler-Chiurazzi, C. LeGuern, M. S. Buckwalter, M. C. Poznansky, and R. F. Sîrbulescu, "The 2022 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, March 30, 2022.", FASEB J, vol. 36, issue 8, pp. e22459, 2022 Aug.
PMCID: PMC9337863 PMID: 35857314