Jennifer L Uhrlaub

Associate Research Scientist, Graduate Student, Nikolich Lab

Jennifer Uhrlaub received a BA from McDaniel College and a Master's in Biotechnology from Johns Hopkins University. She has been with the Nikolich Lab since 2005 working on a diverse array of projects to understand immune determinants of increased susceptibility to acute and chronic viral infection with age. One of her favorite things about Tucson is entertaining on her patio in the middle of “winter."  

Recent Publications

2024

Bradshaw, C. M., T. Georgieva, T. N. Tankersley, T. Taylor-Doyle, L. Johnson, J. L. Uhrlaub, D. Besselsen, and J. Z. Nikolich, "Cutting Edge: Characterization of Low Copy Number Human Angiotensin-Converting Enzyme 2-Transgenic Mice as an Improved Model of SARS-CoV-2 Infection.", J Immunol, vol. 212, issue 4, pp. 523-528, 2024 Feb 15. PMID: 38197714

2022

Sonar, S. Ashok, J. L. Uhrlaub, C. P. Coplen, G. D. Sempowski, J. A. Dudakov, M. R. M. van den Brink, B. J. Lafleur, M. Jergović, and J. Nikolich-Zugich, "Early age-related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging.", Proc Natl Acad Sci U S A, vol. 119, issue 17, pp. e2121028119, 2022 Apr 26. PMCID: PMC9169949  PMID: 35439062
Akarapipad, P., K. Kaarj, L. E. Breshears, K. Sosnowski, J. Baker, B. T. Nguyen, C. Eades, J. L. Uhrlaub, G. Quirk, J. Nikolich-Zugich, et al., "Smartphone-based sensitive detection of SARS-CoV-2 from saline gargle samples via flow profile analysis on a paper microfluidic chip.", Biosens Bioelectron, vol. 207, pp. 114192, 2022 Jul 01. PMCID: PMC8926431  PMID: 35334331
Pugh, J. L., C. P. Coplen, A. S. Sukhina, J. L. Uhrlaub, J. Padilla-Torres, T. Hayashi, and J. Nikolich-Zugich, "Lifelong cytomegalovirus and early-LIFE irradiation synergistically potentiate age-related defects in response to vaccination and infection.", Aging Cell, vol. 21, issue 7, pp. e13648, 2022 Jul. PMCID: PMC9282846  PMID: 35657768
Jergović, M., J. L. Uhrlaub, M. Watanabe, C. M. Bradshaw, L. M. White, B. J. Lafleur, T. Edwards, R. Sprissler, M. Worobey, D. Bhattacharya, et al., "Competent immune responses to SARS-CoV-2 variants in older adults following two doses of mRNA vaccination.", Nat Commun, vol. 13, issue 1, pp. 2891, 2022 May 24. PMCID: PMC9130515  PMID: 35610270
Jergović, M., C. P. Coplen, J. L. Uhrlaub, S. C. Beitel, J. L. Burgess, K. Lutrick, K. D. Ellingson, M. Watanabe, and J. Nikolich-Zugich, "Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved.", J Immunol, vol. 208, issue 11, pp. 2461-2465, 2022 Jun 01. PMCID: PMC9179171  PMID: 35562119
Breshears, L. E., B. T. Nguyen, P. Akarapipad, K. Sosnowski, K. Kaarj, G. Quirk, J. L. Uhrlaub, J. Nikolich-Zugich, M. Worobey, and J-Y. Yoon, "Sensitive, smartphone-based SARS-CoV-2 detection from clinical saline gargle samples.", PNAS Nexus, vol. 1, issue 1, pp. pgac028, 2022 Mar. PMCID: PMC9013775  PMID: 35450423
Uhrlaub, J. L., M. Jergović, C. M. Bradshaw, S. Sonar, C. P. Coplen, J. Dudakov, K. O. Murray, M. C. Lanteri, M. P. Busch, M. R. M. van den Brink, et al., "Quantitative restoration of immune defense in old animals determined by naive antigen-specific CD8 T-cell numbers.", Aging Cell, vol. 21, issue 4, pp. e13582, 2022 Apr. PMCID: PMC9009107  PMID: 35289071
Sylvester, M. A., D. P. Pollow, C. Moffett, W. Nunez, J. L. Uhrlaub, J. Nikolich-Zugich, and H. L. Brooks, "Splenocyte transfer from hypertensive donors eliminates premenopausal female protection from ANG II-induced hypertension.", Am J Physiol Renal Physiol, vol. 322, issue 3, pp. F245-F257, 2022 Mar 01. PMCID: PMC8858666  PMID: 35001661
Kim, S., P. Akarapipad, B. T. Nguyen, L. E. Breshears, K. Sosnowski, J. Baker, J. L. Uhrlaub, J. Nikolich-Zugich, and J-Y. Yoon, "Direct capture and smartphone quantification of airborne SARS-CoV-2 on a paper microfluidic chip.", Biosens Bioelectron, vol. 200, pp. 113912, 2022 Mar 15. PMCID: PMC8701770  PMID: 34973565