Jennifer L Uhrlaub
Associate Research Scientist
Jennifer Uhrlaub received a BA from McDaniel College and a Master's in Biotechnology from Johns Hopkins University. She has been with the Nikolich Lab since 2005 working on a diverse array of projects to understand immune determinants of increased susceptibility to acute and chronic viral infection with age. One of her favorite things about Tucson is entertaining on her patio in the middle of “winter."
Recent Publications
2021
Iwanski, J., S. G. Kazmouz, S. Li, B. Stansfield, T. T. Salem, S. Perez-Miller, T. Kazui, L. Jena, J. L. Uhrlaub, S. Lick, et al., "Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells.", Stem Cell Reports, 2021 Sep 01.
PMID: 34525378
2020
Ripperger, T. J., J. L. Uhrlaub, M. Watanabe, R. Wong, Y. Castaneda, H. A. Pizzato, M. R. Thompson, C. Bradshaw, C. C. Weinkauf, C. Bime, et al., "Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity.", Immunity, 2020 Oct 14.
PMID: 33129373
Wong, R., J. A. Belk, J. Govero, J. L. Uhrlaub, D. Reinartz, H. Zhao, J. M. Errico, L. D'Souza, T. J. Ripperger, J. Nikolich-Zugich, et al., "Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses.", Immunity, 2020 Oct 02.
PMID: 33010224
2019
Thompson, H. L., M. J. Smithey, J. L. Uhrlaub, I. Jeftić, M. Jergović, S. E. White, N. Currier, A. M. Lang, A. Okoye, B. Park, et al., "Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.", Aging Cell, vol. 18, issue 1, pp. e12865, 2019 Feb.
PMCID: PMC6351843 PMID: 30430748
2018
Deshpande, N. R., J. L. Uhrlaub, S. Sing Way, J. Nikolich-Zugich, and M. S. Kuhns, "A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.", PLoS One, vol. 13, issue 6, pp. e0198354, 2018.
PMCID: PMC5986155 PMID: 29864157
2017
Uhrlaub, J. L., M. J. Smithey, and J. Nikolich-Zugich, "Cutting Edge: The Aging Immune System Reveals the Biological Impact of Direct Antigen Presentation on CD8 T Cell Responses.", J Immunol, vol. 199, issue 2, pp. 403-407, 2017 07 15.
PMCID: PMC5520673 PMID: 28615415
2016
Uhrlaub, J. L., V. Pulko, V. R. DeFilippis, R. Broeckel, D. N. Streblow, G. D. Coleman, B. S. Park, J. F. Lindo, I. Vickers, J. J. Anzinger, et al., "Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.", PLoS Pathog, vol. 12, issue 10, pp. e1005891, 2016 Oct.
PMCID: PMC5063327 PMID: 27736984
Pugh, J. L., S. A. Foster, A. S. Sukhina, J. Petravic, J. L. Uhrlaub, J. Padilla-Torres, T. Hayashi, K. Nakachi, M. J. Smithey, and J. Nikolich-Zugich, "Acute systemic DNA damage in youth does not impair immune defense with aging.", Aging Cell, vol. 15, issue 4, pp. 686-93, 2016 08.
PMCID: PMC4933672 PMID: 27072188
2015
Marandu, T. F., J. D. Oduro, L. Borkner, I. Dekhtiarenko, J. L. Uhrlaub, A. Drabig, A. Kröger, J. Nikolich-Zugich, and L. Cičin-Šain, "Immune Protection against Virus Challenge in Aging Mice Is Not Affected by Latent Herpesviral Infections.", J Virol, vol. 89, issue 22, pp. 11715-7, 2015 Nov.
PMCID: PMC4645637 PMID: 26339051
Goldberg, E. L., M. J. Romero-Aleshire, K. R. Renkema, M. S. Ventevogel, W. M. Chew, J. L. Uhrlaub, M. J. Smithey, K. H. Limesand, G. D. Sempowski, H. L. Brooks, et al., "Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.", Aging Cell, vol. 14, issue 1, pp. 130-8, 2015 Feb.
PMCID: PMC4326902 PMID: 25424641