Felicia Goodrum, PhD

Professor, Immunobiology
Director, Graduate Program in Immunobiology
Professor, BIO5 Institute
Professor, Cellular and Molecular Medicine
Professor, Molecular and Cellular Biology
Professor, Cancer Biology-GIDP
Professor, Genetics-GIDP

Felicia Goodrum graduated with her Ph.D. from Wake Forest University and then trained as a postdoctoral fellow with Thomas Shenk at Princeton University where she was a Leukemia and Lymphoma Society Fellow and Special Fellow. In 2006, Dr. Goodrum joined the faculty at the University of Arizona and BIO5 Institute. Dr. Goodrum is the recipient of the Howard Temin Award, the Pew Scholar in Biomedical Sciences Award and the Presidential Award for Early Career Scientists and Engineers. Dr. Goodrum’s work throughout her career has focused on complex interaction between DNA viruses and their host. 

Leadership Roles Faculty Student Advisor, Immunobiology Recipient, Presidential Early Career Award for Scientists and Engineers Leader, research lab Active Participant, building the Immunobiology graduate program

Degrees
  • BS: Virgina Tech - 1992
  • PhD: Wake Forest University School of Medicine - 1998
Fellowship
  • Postdoctoral fellow: Princeton University, Department of Molecular Biology

Recent Publications

2020

Rak, M. A., J. Buehler, S. Zeltzer, J. Reitsma, B. Molina, S. Terhune, and F. Goodrum, "Erratum for Rak et al., "Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency".", J Virol, vol. 94, issue 7, 2020 03 17. PMCID: PMC7081901  PMID: 32184335
Hancock, M. H., J. Mitchell, F. D. Goodrum, and J. A. Nelson, "Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways.", mSphere, vol. 5, issue 4, 2020 Aug 05. PMCID: PMC7407068  PMID: 32759334
Hale, A. E., D. Collins-McMillen, E. M. Lenarcic, S. Igarashi, J. P. Kamil, F. Goodrum, and N. J. Moorman, "FOXO transcription factors activate alternative major immediate early promoters to induce human cytomegalovirus reactivation.", Proc Natl Acad Sci U S A, vol. 117, issue 31, pp. 18764-18770, 2020 08 04. PMCID: PMC7414233  PMID: 32694203
Mlera, L., M. Moy, K. Maness, L. N. Tran, and F. D. Goodrum, "The Role of the Human Cytomegalovirus Gene Locus in Latency and Reactivation.", Viruses, vol. 12, issue 7, 2020 07 01. PMCID: PMC7411667  PMID: 32630219
Chaturvedi, S., J. Klein, N. Vardi, C. Bolovan-Fritts, M. Wolf, K. Du, L. Mlera, M. Calvert, N. J. Moorman, F. Goodrum, et al., "A molecular mechanism for probabilistic bet hedging and its role in viral latency.", Proc Natl Acad Sci U S A, vol. 117, issue 29, pp. 17240-17248, 2020 07 21. PMCID: PMC7382263  PMID: 32632017
Crawford, L. B., R. Tempel, D. N. Streblow, A. D. Yurochko, F. D. Goodrum, J. A. Nelson, and P. Caposio, "Human Cytomegalovirus Infection Suppresses CD34 Progenitor Cell Engraftment in Humanized Mice.", Microorganisms, vol. 8, issue 4, 2020 Apr 06. PMCID: PMC7232458  PMID: 32268565

2019

Buehler, J., E. Carpenter, S. Zeltzer, S. Igarashi, M. Rak, I. Mikell, J. A. Nelson, and F. Goodrum, "Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency.", PLoS Pathog, vol. 15, issue 11, pp. e1008037, 2019 11. PMCID: PMC6855412  PMID: 31725811
Mikell, I., L. B. Crawford, M. H. Hancock, J. Mitchell, J. Buehler, F. Goodrum, and J. A. Nelson, "HCMV miR-US22 down-regulation of EGR-1 regulates CD34+ hematopoietic progenitor cell proliferation and viral reactivation.", PLoS Pathog, vol. 15, issue 11, pp. e1007854, 2019 11. PMCID: PMC6855405  PMID: 31725809

2018

Collins-McMillen, D., J. Buehler, M. Peppenelli, and F. Goodrum, "Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and Reactivation.", Viruses, vol. 10, issue 8, 2018 08 20. PMCID: PMC6116278  PMID: 30127257
Rak, M. A., J. Buehler, S. Zeltzer, J. Reitsma, B. Molina, S. Terhune, and F. Goodrum, "Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency.", J Virol, vol. 92, issue 20, 2018 10 15. PMCID: PMC6158428  PMID: 30089695