Jennifer Frye
Assistant Scientific Investigator
Jen Frye received her Bachelor’s Degree in Ecology and Evolutionary Biology from The University of Arizona. In the Doyle lab, Jen employs her extensive research background to investigate the inflammatory response to stroke in humans as well as different rodent models. In her spare time, Jen enjoys football, wakeboarding, and spending time with her family.
Recent Publications
2025
Arizanovska, D., G. F. Bush Iii, C. A. Dallera, O. O. Folorunso, J. B. Frye, K. P. Doyle, J. R. Jagid, H. Wolosker, B. A. Monaco, J. Graciolli Cordeiro, et al., "Cognitive loss after brain trauma results from sex-specific activation of synaptic pruning processes.", Brain, 2025 Aug 12.
PMID: 40796363
Bartlett, M. J., R. P. Erickson, J. Frye, K. P. Doyle, P. W. Pires, and M. H. Witte, "Manual lymph drainage massage of the head and neck improves cognition and reduces pathological biomarkers in the mouse model of Alzheimers disease.", bioRxiv, 2025 Aug 12.
PMCID: PMC12363786 PMID: 40832216
Brezzo, G., K. A. Zera, D. E. Straus, J. E. Goertz, S. H. Loppi, R. R. Crumpacker, J. B. Frye, D. A. Becktel, M. Isabel Cuartero, A. García Culebras, et al., "Assessing post-stroke cognition in pre-clinical models: Lessons and recommendations from a multi-center study.", J Cereb Blood Flow Metab, pp. 271678X251400241, 2025 Dec 07.
PMCID: PMC12685733 PMID: 41355059
2020
Zbesko, J. C., J. Beischel Frye, D. A. Becktel, D. K. Gerardo, J. Stokes, K. Calderon, T-V. V. Nguyen, D. Bhattacharya, and K. P. Doyle, "IgA natural antibodies are produced following T-cell independent B-cell activation following stroke.", Brain Behav Immun, 2020 Sep 18.
PMID: 32956832
2018
Zbesko, J. C., T-V. V. Nguyen, T. Yang, J. Beischel Frye, O. Hussain, M. Hayes, A. Chung, A. W Day, K. Stepanovic, M. Krumberger, et al., "Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts.", Neurobiol Dis, vol. 112, pp. 63-78, 2018 Jan 10.
PMID: 29331263