Publications

2014

Pickard, J. M., C. F. Maurice, M. A. Kinnebrew, M. C. Abt, D. Schenten, T. V. Golovkina, S. R. Bogatyrev, R. F. Ismagilov, E. G. Pamer, P. J. Turnbaugh, et al., "Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness.", Nature, vol. 514, issue 7524, pp. 638-41, 2014 Oct 30. PMCID: PMC4214913  PMID: 25274297
Nish, S. A., D. Schenten, T. F Wunderlich, S. D. Pope, Y. Gao, N. Hoshi, S. Yu, X. Yan, H. Kyu Lee, L. Pasman, et al., "T cell-intrinsic role of IL-6 signaling in primary and memory responses.", Elife, vol. 3, pp. e01949, 2014. PMCID: PMC4046568  PMID: 24842874
Schenten, D., S. A. Nish, S. Yu, X. Yan, H. Kyu Lee, I. Brodsky, L. Pasman, B. Yordy, T. F Wunderlich, J. C. Brüning, et al., "Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.", Immunity, vol. 40, issue 1, pp. 78-90, 2014 Jan 16. PMCID: PMC4445716  PMID: 24439266
Heger, K., K. Fierens, C. J Vahl, A. Aszodi, K. Peschke, D. Schenten, H. Hammad, R. Beyaert, D. Saur, G. van Loo, et al., "A20-deficient mast cells exacerbate inflammatory responses in vivo.", PLoS Biol, vol. 12, issue 1, pp. e1001762, 2014 Jan. PMCID: PMC3891641  PMID: 24453940

2013

Palm, N. W., R. K. Rosenstein, S. Yu, D. D. Schenten, E. Florsheim, and R. Medzhitov, "Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity.", Immunity, vol. 39, issue 5, pp. 976-85, 2013 Nov 14. PMCID: PMC3852615  PMID: 24210353
Teichmann, L. L., D. Schenten, R. Medzhitov, M. Kashgarian, and M. J. Shlomchik, "Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus.", Immunity, vol. 38, issue 3, pp. 528-40, 2013 Mar 21. PMCID: PMC3638041  PMID: 23499488

2012

Cataisson, C., R. Salcedo, S. Hakim, A. B Moffitt, L. Wright, M. Yi, R. Stephens, R-M. Dai, L. Lyakh, D. Schenten, et al., "IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis.", J Exp Med, vol. 209, issue 9, pp. 1689-702, 2012 Aug 27. PMCID: PMC3428947  PMID: 22908325
Saribasak, H., R. W. Maul, Z. Cao, W. W. Yang, D. Schenten, S. Kracker, and P. J. Gearhart, "DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.", J Exp Med, vol. 209, issue 6, pp. 1075-81, 2012 Jun 4. PMCID: PMC3371727  PMID: 22615128
Haley, K., B. Z. Igyártó, D. Ortner, A. Bobr, S. Kashem, D. Schenten, and D. H. Kaplan, "Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration.", J Immunol, vol. 188, issue 9, pp. 4334-9, 2012 May 1. PMCID: PMC3331889  PMID: 22442445
Song, Y., H. Shen, D. Schenten, P. Shan, P. J. Lee, and D. R. Goldstein, "Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells.", Arterioscler Thromb Vasc Biol, vol. 32, issue 1, pp. 103-9, 2012 Jan. PMCID: PMC3241880  PMID: 22034510
Hoshi, N., D. Schenten, S. A. Nish, Z. Walther, N. Gagliani, R. A. Flavell, B. Reizis, Z. Shen, J. G. Fox, A. Iwasaki, et al., "MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice.", Nat Commun, vol. 3, pp. 1120, 2012. PMCID: PMC3521499  PMID: 23047678

2011

Schenten, D., and R. Medzhitov, "The control of adaptive immune responses by the innate immune system.", Adv Immunol, vol. 109, pp. 87-124, 2011. PMID: 21569913
Chu, Y., C. J Vahl, D. Kumar, K. Heger, A. Bertossi, E. Wójtowicz, V. Soberon, D. Schenten, B. Mack, M. Reutelshöfer, et al., "B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.", Blood, vol. 117, issue 7, pp. 2227-36, 2011 Feb 17. PMID: 21088135

2009

Kleinridders, A., D. Schenten, C. A Könner, B. F. Belgardt, J. Mauer, T. Okamura, T. F Wunderlich, R. Medzhitov, and J. C. Brüning, "MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.", Cell Metab, vol. 10, issue 4, pp. 249-59, 2009 Oct. PMCID: PMC3898351  PMID: 19808018
Schenten, D., S. Kracker, G. Esposito, S. Franco, U. Klein, M. Murphy, F. W. Alt, and K. Rajewsky, "Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.", J Exp Med, vol. 206, issue 2, pp. 477-90, 2009 Feb 16. PMCID: PMC2646585  PMID: 19204108

2006

Schenten, D., A. Egert, M. Pasparakis, and K. Rajewsky, "M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice.", Blood, vol. 107, issue 12, pp. 4849-56, 2006 Jun 15. PMCID: PMC1895815  PMID: 16493007

2002

Schenten, D., V. L. Gerlach, C. Guo, S. Velasco-Miguel, C. L. Hladik, C. L. White, E. C. Friedberg, K. Rajewsky, and G. Esposito, "DNA polymerase kappa deficiency does not affect somatic hypermutation in mice.", Eur J Immunol, vol. 32, issue 11, pp. 3152-60, 2002 Nov. PMID: 12555660

2000

Bannert, N., D. Schenten, S. Craig, and J. Sodroski, "The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.", J Virol, vol. 74, issue 23, pp. 10984-93, 2000 Dec. PMCID: PMC113178  PMID: 11069993

1999

Schenten, D., L. Marcon, G. B. Karlsson, C. Parolin, T. Kodama, N. Gerard, and J. Sodroski, "Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells.", J Virol, vol. 73, issue 7, pp. 5373-80, 1999 Jul. PMCID: PMC112593  PMID: 10364284
Etemad-Moghadam, B., Y. Sun, E. K. Nicholson, G. B. Karlsson, D. Schenten, and J. Sodroski, "Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo.", J Virol, vol. 73, issue 10, pp. 8873-9, 1999 Oct. PMCID: PMC112913  PMID: 10482646

1998

Etemad-Moghadam, B., G. B. Karlsson, M. Halloran, Y. Sun, D. Schenten, M. Fernandes, N. L. Letvin, and J. Sodroski, "Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys.", J Virol, vol. 72, issue 10, pp. 8437-45, 1998 Oct. PMCID: PMC110239  PMID: 9733899
Karlsson, G. B., M. Halloran, D. Schenten, J. Lee, P. Racz, K. Tenner-Racz, J. Manola, R. Gelman, B. Etemad-Moghadam, E. Desjardins, et al., "The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.", J Exp Med, vol. 188, issue 6, pp. 1159-71, 1998 Sep 21. PMCID: PMC2212530  PMID: 9743534