Publications

2015

Purdy, J. G., T. Shenk, and J. D. Rabinowitz, "Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication.", Cell Rep, vol. 10, issue 8, pp. 1375-85, 2015 Mar 3. PMCID: PMC4354725  PMID: 25732827

2014

Hwang, J., J. G. Purdy, K. Wu, J. D. Rabinowitz, and T. Shenk, "Estrogen-related receptor α is required for efficient human cytomegalovirus replication.", Proc Natl Acad Sci U S A, vol. 111, issue 52, pp. E5706-15, 2014 Dec 30. PMCID: PMC4284536  PMID: 25512541
England, M. R., J. G. Purdy, I. J. Ropson, P. M. Dalessio, and R. C. Craven, "Potential role for CA-SP in nucleating retroviral capsid maturation.", J Virol, vol. 88, issue 13, pp. 7170-7, 2014 Jul. PMCID: PMC4054415  PMID: 24719425

2013

Grady, S. L., J. G. Purdy, J. D. Rabinowitz, and T. Shenk, "Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection.", Proc Natl Acad Sci U S A, vol. 110, issue 51, pp. E5006-15, 2013 Dec 17. PMCID: PMC3870743  PMID: 24297925
Koyuncu, E., J. G. Purdy, J. D. Rabinowitz, and T. Shenk, "Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny.", PLoS Pathog, vol. 9, issue 5, pp. e1003333, 2013. PMCID: PMC3656100  PMID: 23696731

2011

Rabinowitz, J. D., J. G. Purdy, L. Vastag, T. Shenk, and E. Koyuncu, "Metabolomics in drug target discovery.", Cold Spring Harb Symp Quant Biol, vol. 76, pp. 235-46, 2011. PMCID: PMC4084595  PMID: 22114327

2010

Butan, C., P. M. Lokhandwala, J. G. Purdy, G. Cardone, R. C. Craven, and A. C. Steven, "Suppression of a morphogenic mutant in Rous sarcoma virus capsid protein by a second-site mutation: a cryoelectron tomography study.", J Virol, vol. 84, issue 13, pp. 6377-86, 2010 Jul. PMCID: PMC2903260  PMID: 20427531

2009

Purdy, J. G., J. M. Flanagan, I. J. Ropson, and R. C. Craven, "Retroviral capsid assembly: a role for the CA dimer in initiation.", J Mol Biol, vol. 389, issue 2, pp. 438-51, 2009 Jun 5. PMCID: PMC2996723  PMID: 19361521
Cardone, G., J. G. Purdy, N. Cheng, R. C. Craven, and A. C. Steven, "Visualization of a missing link in retrovirus capsid assembly.", Nature, vol. 457, issue 7230, pp. 694-8, 2009 Feb 5. PMCID: PMC2721793  PMID: 19194444

2008

Purdy, J. G., J. M. Flanagan, I. J. Ropson, K. E. Rennoll-Bankert, and R. C. Craven, "Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly.", J Virol, vol. 82, issue 12, pp. 5951-61, 2008 Jun. PMCID: PMC2395126  PMID: 18400856