Publications

2016

Cabral, C. M., S. Tuladhar, H. K. Dietrich, E. Nguyen, W. R. MacDonald, T. Trivedi, A. Devineni, and A. A. Koshy, "Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii.", PLoS Pathog, vol. 12, issue 2, pp. e1005447, 2016 Feb. PMCID: PMC4760770  PMID: 26895155
Hidano, S., L. M. Randall, L. Dawson, H. K. Dietrich, C. Konradt, P. J. Klover, B. John, T. H. Harris, Q. Fang, B. Turek, et al., "STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System.", MBio, vol. 7, issue 6, 2016 Nov 08. PMCID: PMC5101356  PMID: 27834206
Konradt, C., N. Ueno, D. A. Christian, J. H. Delong, G. Harms Pritchard, J. Herz, D. J. Bzik, A. A. Koshy, D. B. McGavern, M. B. Lodoen, et al., "Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system.", Nat Microbiol, vol. 1, pp. 16001, 2016 Feb 15. PMCID: PMC4966557  PMID: 27572166

2014

Dupont, C. D., D. A. Christian, E. M. Selleck, M. Pepper, M. Leney-Greene, G. Harms Pritchard, A. A. Koshy, S. Wagage, M. A. Reuter, D. L Sibley, et al., "Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.", PLoS Pathog, vol. 10, issue 4, pp. e1004047, 2014 Apr. PMCID: PMC3983043  PMID: 24722202
Cekanaviciute, E., H. K. Dietrich, R. C. Axtell, A. M. Williams, R. Egusquiza, K. M. Wai, A. A. Koshy, and M. S. Buckwalter, "Astrocytic TGF-β signaling limits inflammation and reduces neuronal damage during central nervous system Toxoplasma infection.", J Immunol, vol. 193, issue 1, pp. 139-49, 2014 Jul 1. PMCID: PMC4075480  PMID: 24860191
Christian, D. A., A. A. Koshy, M. A. Reuter, M. R. Betts, J. C. Boothroyd, and C. A. Hunter, "Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis.", Infect Immun, vol. 82, issue 10, pp. 4056-67, 2014 Oct. PMCID: PMC4187868  PMID: 25024368
Blader, I. J., and A. A. Koshy, "Toxoplasma gondii development of its replicative niche: in its host cell and beyond.", Eukaryot Cell, vol. 13, issue 8, pp. 965-76, 2014 Aug. PMCID: PMC4135789  PMID: 24951442
Han, S-J., H. J. Melichar, J. L. Coombes, S. Wei Chan, A. A. Koshy, J. C. Boothroyd, G. M. Barton, and E. A. Robey, "Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii.", Immunol Cell Biol, vol. 92, issue 10, pp. 872-81, 2014 Nov. PMCID: PMC4245188  PMID: 25155465
Koshy, A. A., and C. M. Cabral, "3-D imaging and analysis of neurons infected in vivo with Toxoplasma gondii.", J Vis Exp, issue 94, 2014. PMCID: PMC4362681  PMID: 25549001

2013

Caffaro, C. E., A. A. Koshy, L. Liu, G. M. Zeiner, C. B. Hirschberg, and J. C. Boothroyd, "A nucleotide sugar transporter involved in glycosylation of the Toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites.", PLoS Pathog, vol. 9, issue 5, pp. e1003331, 2013. PMCID: PMC3642066  PMID: 23658519
Coombes, J. L., B. A. Charsar, S-J. Han, J. Halkias, S. Wei Chan, A. A. Koshy, B. Striepen, and E. A. Robey, "Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.", Proc Natl Acad Sci U S A, vol. 110, issue 21, pp. E1913-22, 2013 May 21. PMCID: PMC3666704  PMID: 23650399

2012

Koshy, A. A., H. K. Dietrich, D. A. Christian, J. H. Melehani, A. J. Shastri, C. A. Hunter, and J. C. Boothroyd, "Toxoplasma co-opts host cells it does not invade.", PLoS Pathog, vol. 8, issue 7, pp. e1002825, 2012. PMCID: PMC3406079  PMID: 22910631

2010

Koshy, A. A., A. E. Fouts, M. B. Lodoen, O. Alkan, H. M. Blau, and J. C. Boothroyd, "Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.", Nat Methods, vol. 7, issue 4, pp. 307-9, 2010 Apr. PMCID: PMC2850821  PMID: 20208532