Publications

2016

Nguyen, T-V. V., J. B. Frye, J. C. Zbesko, K. Stepanovic, M. Hayes, A. Urzua, G. Serrano, T. G. Beach, and K. P. Doyle, "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue.", Acta Neuropathol Commun, vol. 4, issue 1, pp. 100, 2016 Sep 06. PMCID: PMC5011964  PMID: 27600707
Doyle, K. P., and M. S. Buckwalter, "Does B lymphocyte-mediated autoimmunity contribute to post-stroke dementia?", Brain Behav Immun, 2016 Aug 13. PMCID: PMC5305803  PMID: 27531189

2015

Doyle, K. P., L. N. Quach, M. Solé, R. C. Axtell, T-V. V. Nguyen, G. J. Soler-Llavina, S. Jurado, J. Han, L. Steinman, F. M. Longo, et al., "B-Lymphocyte-mediated delayed cognitive impairment following stroke.", J Neurosci, vol. 35, issue 5, pp. 2133-45, 2015 Feb 4. PMCID: PMC4315838  PMID: 25653369
Doyle, K. P., L. N. Quach, H. E. D'Arceuil, and M. S. Buckwalter, "Ferumoxytol administration does not alter infarct volume or the inflammatory response to stroke in mice.", Neurosci Lett, vol. 584, pp. 236-40, 2015 Jan 1. PMCID: PMC4268374  PMID: 25449870

2014

Cekanaviciute, E., N. Fathali, K. P. Doyle, A. M. Williams, J. Han, and M. S. Buckwalter, "Astrocytic transforming growth factor-Beta signaling reduces subacute neuroinflammation after stroke in mice.", Glia, vol. 62, issue 8, pp. 1227-40, 2014 Aug. PMCID: PMC4061255  PMID: 24733756

2012

Pollak, J., K. P. Doyle, L. Mamer, M. Shamloo, and M. S. Buckwalter, "Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model.", Brain Behav, vol. 2, issue 5, pp. 698-706, 2012 Sep. PMCID: PMC3489820  PMID: 23139913
Doyle, K. P., and M. S. Buckwalter, "The double-edged sword of inflammation after stroke: what sharpens each edge?", Ann Neurol, vol. 71, issue 6, pp. 729-31, 2012 Jun. PMID: 22718541
Han, J., J. Pollak, T. Yang, M. R. Siddiqui, K. P. Doyle, K. Taravosh-Lahn, E. Cekanaviciute, A. Han, J. Z. Goodman, B. Jones, et al., "Delayed Administration of a Small Molecule Tropomyosin-Related Kinase B Ligand Promotes Recovery After Hypoxic-Ischemic Stroke.", Stroke, vol. 43, issue 7, pp. 1918-24, 2012 Jul. PMCID: PMC3383889  PMID: 22535263
Doyle, K. P., N. Fathali, M. R. Siddiqui, and M. S. Buckwalter, "Distal hypoxic stroke: A new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit.", J Neurosci Methods, vol. 207, issue 1, pp. 31-40, 2012 May 30. PMCID: PMC3348433  PMID: 22465679
Csiszar, A., A. Podlutsky, N. Podlutskaya, W. E. Sonntag, S. Z. Merlin, E. E. R. Philipp, K. Doyle, A. Davila, F. A. Recchia, P. Ballabh, et al., "Testing the Oxidative Stress Hypothesis of Aging in Primate Fibroblasts: Is There a Correlation Between Species Longevity and Cellular ROS Production?", J Gerontol A Biol Sci Med Sci, vol. 67, issue 8, pp. 841-52, 2012 Aug. PMCID: PMC3403864  PMID: 22219516

2011

Bahjat, F. Rena, R. L. Williams-Karnesky, S. G. Kohama, A. G West, K. P. Doyle, N. S. Lessov, M. D. Spector, T. R. Hobbs, and M. P. Stenzel-Poore, "Proof of Concept: Pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke.", J Cereb Blood Flow Metab, vol. 31, issue 5, pp. 1229-42, 2011 May. PMCID: PMC3099644  PMID: 21285967

2010

Doyle, K. P., E. Cekanaviciute, L. E. Mamer, and M. S. Buckwalter, "TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke.", J Neuroinflammation, vol. 7, pp. 62, 2010. PMCID: PMC2958905  PMID: 20937129

2009

G West, A., K. J. Golshani, K. P. Doyle, N. S. Lessov, T. R. Hobbs, S. G. Kohama, M. M. Pike, C. D. Kroenke, M. R. Grafe, M. D. Spector, et al., "A new model of cortical stroke in the rhesus macaque.", J Cereb Blood Flow Metab, vol. 29, issue 6, pp. 1175-86, 2009 Jun. PMCID: PMC2828874  PMID: 19384334

2008

Doyle, K. P., M. P. Stenzel-Poore, and R. P. Simon, "Mechanisms of ischemic brain damage.", Neuropharmacology, vol. 55, issue 3, pp. 310-8, 2008 Sep. PMCID: PMC2603601  PMID: 18308346
Doyle, K. P., S. L. Stevens, N. S. Lessov, T. Yang, T. M. Ciesielski, R. P. Simon, J. S. King, and M. P. Stenzel-Poore, "Nasal administration of osteopontin peptide mimetics confers robust neuroprotection in stroke.", J Cereb Blood Flow Metab, vol. 28, issue 6, pp. 1235-48, 2008 Jun. PMID: 18364727

2007

Doyle, K. P., K. L. Suchland, T. M. P. Ciesielski, N. S. Lessov, D. K. Grandy, T. S. Scanlan, and M. P. Stenzel-Poore, "Novel Thyroxine Derivatives, Thyronamine and 3-iodothyronamine, Induce Transient Hypothermia and Marked Neuroprotection Against Stroke Injury.", Stroke, vol. 38, issue 9, pp. 2569-76, 2007 Sep. PMID: 17690312

2005

Meller, R., S. L. Stevens, M. Minami, J. A. Cameron, S. King, H. Rosenzweig, K. Doyle, N. S. Lessov, R. P. Simon, and M. P. Stenzel-Poore, "Neuroprotection by Osteopontin in Stroke.", J Cereb Blood Flow Metab, vol. 25, issue 2, pp. 217-25, 2005 Feb. PMID: 15678124

2003

Doyle, K. P., R. P. Simon, A. Snyder, and M. P. Stenzel-Poore, "Working with GFP in the Brain.", Biotechniques, vol. 34, issue 3, pp. 492-4, 2003 Mar. PMID: 12669698