Shraddha Tuladhar

Graduate Student

Shraddha earned her Bachelors in Science from Salem College. Before pursuing graduate studies, she worked as a research assistant in the lab of Dr. Frelinger, studying immune response to Francisella tularensis. In the Koshy lab, she is working on dissecting Toxoplasma strain-specific CNS immune responses. The goal of her thesis work is to use the mouse model of CNS toxoplasmosis to better understand how two different clinically relevant canonical strains of Toxoplasma (type II and type III) can cause different CNS outcomes.

Recent Publications

2016

Cabral, C. M., S. Tuladhar, H. K. Dietrich, E. Nguyen, W. R. MacDonald, T. Trivedi, A. Devineni, and A. A. Koshy, "Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii.", PLoS Pathog, vol. 12, issue 2, pp. e1005447, 2016 Feb. PMCID: PMC4760770  PMID: 26895155

2015

Roberts, L. M., H. E. Ledvina, S. Tuladhar, D. Rana, S. P. Steele, G. D. Sempowski, and J. A. Frelinger, "Depletion of alveolar macrophages in CD11c diphtheria toxin receptor mice produces an inflammatory response.", Immun Inflamm Dis, vol. 3, issue 2, pp. 71-81, 2015 Jun. PMCID: PMC4444150  PMID: 26029367

2014

Roberts, L. M., S. Tuladhar, S. P. Steele, K. J. Riebe, C-J. Chen, I. R Cumming, S. Seay, R. Frothingham, G. D. Sempowski, T. H. Kawula, et al., "Identification of early interactions between Francisella and the host.", Infect Immun, vol. 82, issue 6, pp. 2504-10, 2014 Jun. PMCID: PMC4019147  PMID: 24686053

2013

Barrigan, L. M., S. Tuladhar, J. C. Brunton, M. D. Woolard, C-J. Chen, D. Saini, R. Frothingham, G. D. Sempowski, T. H. Kawula, and J. A. Frelinger, "Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.", Infect Immun, vol. 81, issue 6, pp. 2028-42, 2013 Jun. PMCID: PMC3676025  PMID: 23529616