Felicia Goodrum Sterling

Associate Professor

Felicia Goodrum graduated with her Ph.D. from Wake Forest University and then trained as a postdoctoral fellow with Thomas Shenk at Princeton University where she was a Leukemia and Lymphoma Society Fellow and Special Fellow. In 2006, Dr. Goodrum joined the faculty at the University of Arizona and BIO5 Institute. Dr. Goodrum is the recipient of the Howard Temin Award, the Pew Scholar in Biomedical Sciences Award and the Presidential Award for Early Career Scientists and Engineers. Dr. Goodrum’s work throughout her career has focused on complex interaction between DNA viruses and their host. 

Leadership Roles Faculty Student Advisor, Immunobiology Recipient, Presidential Early Career Award for Scientists and Engineers Leader, research lab Active Participant, building the Immunobiology graduate program

Degrees
  • BS: Virgina Tech - 1992
  • PhD: Wake Forest University School of Medicine - 1998
Fellowship
  • Postdoctoral fellow: Princeton University, Department of Molecular Biology

Recent Publications

2017

Kim, J. Heon, D. Collins-McMillen, J. C. Buehler, F. D. Goodrum, and A. D. Yurochko, "Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells.", J Virol, vol. 91, issue 5, 2017 Mar 01. PMCID: PMC5309964  PMID: 27974567
Gordon, C. L., M. Miron, J. J. C. Thome, N. Matsuoka, J. Weiner, M. A. Rak, S. Igarashi, T. Granot, H. Lerner, F. Goodrum, et al., "Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection.", J Exp Med, vol. 214, issue 3, pp. 651-667, 2017 Mar 06. PMCID: PMC5339671  PMID: 28130404
Cheng, S., K. Caviness, J. Buehler, M. Smithey, J. Nikolich-Zugich, and F. Goodrum, "Transcriptome-wide characterization of human cytomegalovirus in natural infection and experimental latency.", Proc Natl Acad Sci U S A, vol. 114, issue 49, pp. E10586-E10595, 2017 Dec 05. PMCID: PMC5724264  PMID: 29158406

2016

Caviness, K., F. Bughio, L. B. Crawford, D. N. Streblow, J. A. Nelson, P. Caposio, and F. Goodrum, "Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency.", MBio, vol. 7, issue 2, pp. e01986, 2016 Mar 01. PMCID: PMC4810493  PMID: 26933055
Buehler, J., S. Zeltzer, J. Reitsma, A. Petrucelli, M. Umashankar, M. Rak, P. Zagallo, J. Schroeder, S. Terhune, and F. Goodrum, "Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication.", PLoS Pathog, vol. 12, issue 5, pp. e1005655, 2016 May. PMCID: PMC4878804  PMID: 27218650
Lee, S. Hee, K. Caviness, E. R. Albright, J-H. Lee, C. B. Gelbmann, M. Rak, F. Goodrum, and R. F. Kalejta, "Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency.", J Virol, vol. 90, issue 20, pp. 9483-94, 2016 10 15. PMCID: PMC5044833  PMID: 27512069

2015

Bughio, F., M. Umashankar, J. Wilson, and F. Goodrum, "Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells.", J Virol, vol. 89, issue 13, pp. 6536-50, 2015 Jul. PMCID: PMC4468499  PMID: 25878111
Goodrum, F., and F. Bughio, "Viral infection at the endothelium.", Oncotarget, vol. 6, issue 29, pp. 26541-2, 2015 Sep 29. PMCID: PMC4694926  PMID: 26309089

2014

Li, G., M. Rak, C. C. Nguyen, M. Umashankar, F. D. Goodrum, and J. P. Kamil, "An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle.", J Virol, vol. 88, issue 11, pp. 6047-60, 2014 Jun. PMCID: PMC4093856  PMID: 24623439
Caviness, K., L. Cicchini, M. Rak, M. Umashankar, and F. Goodrum, "Complex expression of the UL136 gene of human cytomegalovirus results in multiple protein isoforms with unique roles in replication.", J Virol, vol. 88, issue 24, pp. 14412-25, 2014 Dec. PMCID: PMC4249117  PMID: 25297993