Deepta Bhattacharya

Associate Professor

Deepta Bhattacharya received his PhD from the University of California, Berkeley, studying the role of the NF-kB transcription factor in survival and B cell class switching. For his postdoctoral fellowship, he trained at Stanford University, studying the cell biology of hematopoietic stem cells and their differentiated progeny. In 2008, he began his own lab at Washington University in St. Louis, first as an Assistant Professor and then as a tenured Associate Professor.  Dr. Bhattacharya returned in 2017 to his birthplace of Tucson to join the Department of Immunobiology, where his lab continues to study both stem cells and antibody responses to infections and vaccines.

Degrees
  • BS: Indiana University
  • PhD: University of California, Berkeley
Fellowship
  • Post-doctoral Fellow: Stanford University

Recent Publications

2018

Lam, W. Y., and D. Bhattacharya, "Metabolic Links between Plasma Cell Survival, Secretion, and Stress.", Trends Immunol, vol. 39, issue 1, pp. 19-27, 2018 Jan. PMCID: PMC5748358  PMID: 28919256
Lam, W. Y., A. Jash, C-H. Yao, L. D'Souza, R. Wong, R. M. Nunley, G. P. Meares, G. J. Patti, and D. Bhattacharya, "Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function.", Cell Rep, vol. 24, issue 9, pp. 2479-2492.e6, 2018 Aug 28. PMID: 30157439
Adamo, L., L. J. Staloch, C. Rocha-Resende, S. J. Matkovich, W. Jiang, G. Bajpai, C. J. Weinheimer, A. Kovacs, J. D. Schilling, P. M. Barger, et al., "Modulation of subsets of cardiac B lymphocytes improves cardiac function after acute injury.", JCI Insight, vol. 3, issue 11, 2018 Jun 07. PMID: 29875326

2016

He, Z., J. O'Neal, W. C. Wilson, N. Mahajan, J. Luo, Y. Wang, M. Y. Su, L. Lu, J. B. Skeath, D. Bhattacharya, et al., "Deletion of Rb1 induces both hyperproliferation and cell death in murine germinal center B cells.", Exp Hematol, vol. 44, issue 3, pp. 161-5.e4, 2016 Mar. PMCID: PMC4789175  PMID: 26607597
Chou, C., D. J. Verbaro, E. Tonc, M. Holmgren, M. Cella, M. Colonna, D. Bhattacharya, and T. Egawa, "The Transcription Factor AP4 Mediates Resolution of Chronic Viral Infection through Amplification of Germinal Center B Cell Responses.", Immunity, vol. 45, issue 3, pp. 570-82, 2016 Sep 20. PMCID: PMC5037962  PMID: 27566940
Bhattacharya, D., and R. Wong, "The Chosen Few: Only a Subset of Memory B Cells Responds to Secondary Dengue Virus Infections.", EBioMedicine, vol. 12, pp. 12-13, 2016 Oct. PMCID: PMC5078616  PMID: 27743902
Lam, W. Y., A. M. Becker, K. M. Kennerly, R. Wong, J. D. Curtis, E. M. Llufrio, K. S. McCommis, J. Fahrmann, H. A. Pizzato, R. M. Nunley, et al., "Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.", Immunity, vol. 45, issue 1, pp. 60-73, 2016 Jul 19. PMCID: PMC4956536  PMID: 27396958
Jash, A., Y. Wang, F. J. Weisel, C. D. Scharer, J. M. Boss, M. J. Shlomchik, and D. Bhattacharya, "ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.", J Immunol, vol. 197, issue 4, pp. 1159-68, 2016 Aug 15. PMCID: PMC4975986  PMID: 27357154

2015

Becker, A. M., D. J. Callahan, J. M. Richner, J. Choi, J. F. DiPersio, M. S. Diamond, and D. Bhattacharya, "GPR18 Controls Reconstitution of Mouse Small Intestine Intraepithelial Lymphocytes following Bone Marrow Transplantation.", PLoS One, vol. 10, issue 7, pp. e0133854, 2015. PMCID: PMC4510063  PMID: 26197390
Becker, A. M., B. Walcheck, and D. Bhattacharya, "ADAM17 limits the expression of CSF1R on murine hematopoietic progenitors.", Exp Hematol, vol. 43, issue 1, pp. 44-52.e1-3, 2015 Jan. PMCID: PMC4268392  PMID: 25308957