 Mother to Infant transmission of HIV-1 Lab
Molecular mechanisms of HIV-1 mother-infant transmission,
Viral Factors associated with mother to infant transmission,
Genotypic and phenotypic characterization of HIV-1 isolates
involved in other to infant transmission.
Publications
Recent Publications:
- Biological characterization of HIV type 1 envelope V3 regions from mothers and infants associated with perinatal transmission
Erik Matala, Tobias Hahn, Venkat R. K. Yedavalli, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, 17(18):1725-1735, 2001
- Genetic characterization of HIV type 1 gag p17 matrix genes in isolates from infected mothers lacking perinatal transmission
Tobias Hahn, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, 17(17):1673-1680, 2001
- Molecular Characterization of HIV Type 1 vpuGenes from in Mothers and Infants after Perinatal Transmission
Venkat R. K. Yedavalli, Mohammad Husain, Andrew Horodner, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, 17(11):1089-1098, 2001
- Low Conservation of Functional Domains of HIV Type 1 vif and vpr Genes in Infected Mothers Correlates with Lack of Vertical Transmission
Venkat R. K. Yedavalli, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, 17(10):911-923, 2001
- Characterization of HIV Type 1 tat Sequences Associated with Perinatal Transmission
Mohammad Husain, Tobias Hahn, Venkat R. K. Yedavalli, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, 17(8):765-773, 2001
- Molecular Mechanisms of Human Immunodeficiency Virus Type 1 Mother-Infant Transmission
Nafees Ahmad
Adv. Pharm, v49:387-415 2000
- Limited Heterogeneity of HIV Type 1 in Infected Mothers Correlates with Lack of Vertical Transmission
Erik Matala, Keith A. Crandall, Raymond C. Baker, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, Oct 10;16(15):1481-9 October 2000
Earlier Publications:
- Characterization of Mother-Infant HIV Type 1 gag p17 Sequences Associated with Perinatal Transmission
Tobias Hahn, Erik Matala, Colombe Chappey, and Nafees Ahmad
AIDS Res. and Hum. Retroviruses, v.15, #10, July 1999, pp. 875-888
- Characterization of Human Immunodeficiency Virus Type-1 Involved in Maternal-Fetal Transmission
Nafees Ahmad, Erik Matala, R. K. Venkat Yedavalli, Tobias Hahn, and Mohammad Husain
Advances in Animal Virology, pp.351-370. 1998 Oxford and IBH Publishing Co. Ltd., New Delhi/Calcutta
- Maintenance of an Intact Human Immunodeficiency Virus Type 1 vpr Gene Following Mother-to-Infant Transmission
Venkat R. K. Yedavalli, Colombe Chappey, and Nafees Ahmad
Journal of Virology, August 1998, p. 6937-6943, Vol. 72, No. 8
- Conservation of an Intact vif Gene of Human Immunodeficiency virus Type 1 during Maternal-Fetal Transmission
Venkat R. K. Yedavalli, Colombe Chappey, Erik Matala, and Nafees Ahmad
Journal of Virology v. 72, p. 1092-1102, Feb 1998
- Maternal-Fetal Transmissions of Human Immunodeficiency Virus
Nafees Ahmad
Journal of Biomedical Science
1996; 3: 238-250
- Genetic Analysis of Immunodeficiency Virus Type 1 Envelope V3 Region Isolates from Mothers and Infants after Perinatal Transmission
Nafees Ahmad, Bahige M. Baroudy, Raymond C. Baker, and Colombe Chappey
Journal of Virology
Feb. 1995, p. 1001-1012
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Lab Personnel
Nafees Ahmad, PhD
Director (PI)
Joined the Department of Microbiology and Immunology, College of Medicine, University of Arizona in September 1994. Received my B.Sc. (Hons), M.Sc. from the Aligarh Muslim University, Aligarh, India and M.Phil. and Ph.D. from the Central Drug Research Institute, Lucknow, India. Moved to the United States in 1985 for a post-doctoral training at the National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland. Worked on Regulation of human immunodeficiency virus type 1 (HIV-1) gene expression from 1985 to 1990. Joined the J. N. Gamble Institute of Medical Research, Cincinnati, Ohio in September 1990. Worked there on Molecular Mechanisms of HIV-1 Mother-Infant Transmission and Molecular Biology of Hepatitis C Virus. Joined the Department of Microbiology and Immunology of the University of Arizona College of Medicine in September 1994. My teaching responsibilities are: Medical Virology to M.D. second year students and Molecular Virology and Tumor Virology to Ph.D. students. The main emphasis of my laboratory is to understand the molecular mechanisms of HIV-1 mother-infant transmission. Each graduate student in the lab. has his own project.
Graduate-Students:
Rajesh Ramakrishnan:
I am a graduate student at the University of Arizona,Tucson. After about 5 years working in the pharmaceutical industry in Mumbai,India; I yearned for a change and so I am here. I am working on aspects of mother-infant transmission of HIV virus in Dr. Nafees Ahmad's lab at the Dept.Of Microbiology & Immunology,College of Medicine. Also have a look at my homepage.
Vasudha Sundaravaradan:
I am an international student from India. After studying all over India, I decided to give another country a try. I joined this program in July 2000 with the intention of working with Dr. Ahmad. I did my Bachelor¹s degree in Microbiology in the cyber city of India- Hyderbad. I did my Master¹s in Biotechnology in Shimla, which is on the foothills of the Himalayas. And the travel bug bit me and I need to go to better places and better things and landed here and happy to find that research is not always frustrating. I am an outgoing person who needs to try most things atleast once - ofcourse with caution.
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Lab Links
Institutional Pages:
Search Tools:
Sequence Interpretation:
- Genquest - FASTA, BLAST
- BCM-SearchLauncher - sequence-search using FASTA, BLAST, BEAUTY, BLOCKS (and derivatives)
- BLOCKS
- BLAST Blastserver: Sanger,
- France
- BCM-SearchLauncher - multiple sequence alignment using MSA, Clustal, PIMA
- ISREC-Page - examine sequences, searching for specific features using SAPS, TMpred, BOXSHADE, Prositescan, PatternFind, Coils
- ProDom - protein domain database
- MOTIF - search a protein for common motifs
- ProteinMotifs - search AA or DNA sequences for your motif
- PredictProtein - server at the EMBL Heidelberg
- TESS - find transcription factorsites
- ExPasy - Enzyme Database
- ReBase - Restriction Enzyme Database
Tools:
UofA Biosciences:
Collaborations:
Journals:
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Lab Tour
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West side of the Main Lab
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Center of the Lab
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East side of the Main lab.
The speed- bumped Apple PPC 6100.
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The oldest lab equipment;
the trusted shaking incubator.
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Inhabitant of the East Side
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