The University of Arizona  
University of Arizona
University of ArizonaDepartment of Immunobiology
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Neil Ampel, MDNeil Ampel, MD

 

Contact Information:

  • Internal Medicine, VAMC
  • Phone: 792-1450

 

Education:

  • University of Oregon, 1977.

 

Research:

Cellular Immunity of Coccidioidomycosis. Coccidioidomycosis is a fungal disease common in the Southwest United States . In humans, an appropriate cellular immune response appear necessary for successful host defense. My laboratory has a long-term interest in the human immune response to coccidioidal infection. Currently, we are exploring the use of multiparametric flow cytometry to assess which coccidioidal antigens might serve as possible human vaccine candidates and are initiating an examination of the cellular immune responses in peripheral blood compared to bronchoalveolar lavage.

 

Publications:

  • Dionne SO, Podany AB, Ruiz YW, Ampel NM, Galgiani JN, Lake DF. Spherules derived from Coccidioides posadasii promote human dendritic cell maturation and activation. Infect Immun, 74:2415-22, 2006.
  • Ampel NM, Hector RF, Lindan CP, Rutherford GW. An archived lot of coccidioidin induces specific delayed-type hypersensitivity and correlates with in vitro assays of coccidioidal cellular immune response. Mycopathologia, 161:67-72, 2006.
  • Bowers JM, Mourani JP, Ampel NM. Fatigue in coccidioidomycosis. Quantification and correlation with clinical, immunological, and nutritional factors. Med Mycol, 44:585-90, 2006.
  • Li L, Dial SM, Schmelz M, Rennels MA, Ampel NM. Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis. Infect Immun, 73:3923-8, 2005.

 

Peer-reviewed publications

Click here to see a listing of Peer-reviewed publications

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