Rod Adam, MD
Professor
Contact Information:
Education:
- University of Illinois, 1981.
Research:
Molecular Parasitology.
The protozoan parasite, Giardia lamblia , undergoes antigenic variation of a set of a cysteine-rich surface proteins (VSP). The laboratory is interested in determining the molecular mechanism(s) controlling the switch in expression from one vsp gene to another, and why only one vsp gene is expressed at a time.
The laboratory is actively participating in a genome project for Giardia . The project will map and determine the DNA sequence of Giardia . We are also interested in genetic structure and change in Giardia . The trophozoites have two nuclei that appear identical. We would like to understand how the inheritance of genetic material via two nuclei is handled.
Publications:
- Xian-Min F., Cao LJ, Adam RD, Zhang XC, and Lu SQ. The catalyzing role of PPDK in Giardia lamblia, Biochemical and Biophysical Research Communications, 367:394-398, 2008.
- Cooper MA., Adam RD., Worobey M., and Sterling CR, Population genetic evidence for recombination in Giardia, Current Biology 17:1984-1988, 2007
- Morrison HG, McArthur AG, Gillin FD, Aley SB, Adam RD, Olsen GJ, ReinerDS, Svard SG, Elmendorf HG, Hehl AB, Samuelson J, Nixon JEJ, Passamaneck NE, Kim UU, Lasek-Nesselquist E, Cipriano MJ, Holder ME, Huse SM, Palm D, Best AA, Reich CI, Nigam A, Prabhu A, Davids BJ, and Sogin ML, Genomic minimalism in the early diverging, intestinal parasite, Giardia lamblia, Science 317:1921-1926, 2007.
- Yee J Tang A, Ritter H, Lau W, Delport D, Page M, Adam RD, Muller M, and Wu G. Core histone genes of Giardia intestinalis: genomic organization, promoter structure, and expression, BMC Molecular Biology, 8:26, 2007.
- Prabhu, A., Morrison HG, Martinez, III CR, and Adam RD. Characterization of the Subtelomeric regions of Giardia lamblia Genome Isolate WBC6, International Journal for Parasitology, 37:503-513, 2007.
Peer-reviewed publications
Click here to see a listing of Peer-reviewed publications
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